Evidence map›Paper›PMID 42701496›Full record

ArticleCurrent developments in nutrition2026

Influence of Protein Intake during Obesity Reduction on Physical Function and Body Habitus in Older Males with Prediabetes: A Pilot Study.

Connie W Bales, Marshall G Miller, Shelley R McDonald, Jessica T Wallis, Leigh Ann Yeager, Richard J Sloane, Kathryn N Porter Starr

Registry-linked trialAbstract read
In one paragraph

Article in Current developments in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03835416 (Enhanced Protein Intake During Obesity Reduction in Older Male Veterans), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03835416 nacompletednot on this map

Enhanced Protein Intake During Obesity Reduction in Older Male Veterans: Differences in Physical Function and Muscle Quality Responses by Race

TypeinterventionalSponsorVA Office of Research and DevelopmentRan2019 to 2024Enrolled105ConditionsPrediabetes, ObesityArmsFoods rich in high quality protein
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Connie W BalesGRECC, Durham VA Health Care System, Durham, NC, United States.
Marshall G MillerCenter for the Study of Aging, School of Medicine, Duke University Medical Center, Durham, NC, United States.
Shelley R McDonaldGRECC, Durham VA Health Care System, Durham, NC, United States.
Jessica T WallisCenter for the Study of Aging, School of Medicine, Duke University Medical Center, Durham, NC, United States.
Leigh Ann YeagerGRECC, Durham VA Health Care System, Durham, NC, United States.
Richard J SloaneGRECC, Durham VA Health Care System, Durham, NC, United States.
Kathryn N Porter StarrGRECC, Durham VA Health Care System, Durham, NC, United States.

Funding

Resource Core 3 - Metabolomics CoreP30AG028716 · NIA · DUKE UNIVERSITY · PI CATHLEEN S COLON-EMERIC, Susan Nicole Hastings · 2006 to 2026
$24.6M
NIA NIH HHS P30 AG028716
6 · The paper itself

Abstract

Background: Weight loss can improve health and function in older adults with obesity but may also accelerate loss of fat-free mass. Older men are underrepresented in obesity intervention trials; thus we tested higher protein intake plus exercise to help preserve muscle mass and physical function during weight loss in men with obesity and prediabetes. Objectives: We evaluated the effects of an enhanced protein weight loss intervention relative to a recommended dietary allowance (RDA)-level protein intervention in older males (veterans) with prediabetes and obesity. Methods: This study was a randomized controlled trial. Equal numbers of participants, males aged >55 y with obesity [body mass index (BMI), in kg/m Results: Baseline characteristics were as follows: BMI = 35.8 ± 4.3, mean age 67.6 ± 7.0 y, and hemoglobin A1c 6.0% ± 0.3%. For the SPPB score, the Enhanced Protein group had a greater benefit at both 3 mo (small Cohen's Conclusions: The results provide preliminary evidence that an enhanced protein regimen can benefit older males with prediabetes, especially with regard to physical function and body composition.This trial was registered at clinicaltrials.gov as NCT03835416.

Indexed as

functionobesity interventionolder adultsprediabetesprotein

Identifiers

PMID42701496
PMCPMC13545418

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.