Evidence map›Paper›PMID 42701464›Full record

ArticleSynthetic and systems biotechnology2027

Ribosome engineering enhances genetic code expansion in

Xiaoxu Chen, Wenlu Shen, Xianqing Chen, Fangfang Zhang, Bo Yang, Zhiyong Yue, Guanghou Zhao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Synthetic and systems biotechnology, 2027. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiaoxu ChenKey Laboratory of Natural Anti-aging Product Mining and Biosynthesis of Shaanxi Higher Education Institutes, College of Medicine, Xi'an International University, Xi'an, 710077, China.
Wenlu ShenSchool of Life Science and Technology, Northwestern Polytechnical University, Xi'an, Shaanxi, 710129, China.
Xianqing ChenKey Laboratory of Natural Anti-aging Product Mining and Biosynthesis of Shaanxi Higher Education Institutes, College of Medicine, Xi'an International University, Xi'an, 710077, China.
Fangfang ZhangKey Laboratory of Natural Anti-aging Product Mining and Biosynthesis of Shaanxi Higher Education Institutes, College of Medicine, Xi'an International University, Xi'an, 710077, China.
Bo YangKey Laboratory of Natural Anti-aging Product Mining and Biosynthesis of Shaanxi Higher Education Institutes, College of Medicine, Xi'an International University, Xi'an, 710077, China.
Zhiyong YueKey Laboratory of Natural Anti-aging Product Mining and Biosynthesis of Shaanxi Higher Education Institutes, College of Medicine, Xi'an International University, Xi'an, 710077, China.
Guanghou ZhaoSchool of Life Science and Technology, Northwestern Polytechnical University, Xi'an, Shaanxi, 710129, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genetic code expansion enables the site-specific installation of noncanonical amino acids (ncAAs) into proteins, but its limited efficiency in eukaryotes remains a major barrier to broader application. Here we establish a visual, plug-and-play screening platform to evolve 18S ribosomal DNA in

Indexed as

Genetic code expansionNoncanonical amino acidRibosome engineeringSaccharomyces cerevisiae

Identifiers

PMID42701464
PMCPMC13545395

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.