ArticleQuantitative imaging in medicine and surgery2026
Characterization of carotid remodeling in gestational hypertension using radiofrequency data-based vessel stiffness analysis and vector flow imaging.
Article in Quantitative imaging in medicine and surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Gestational hypertension (GH) is associated with maternal vascular remodeling; however, the biomechanical and hemodynamic features related to increased carotid intima-media thickness (CIMT) remain insufficiently characterized. This study aimed to evaluate carotid remodeling in women with GH using radiofrequency data-based quantitative vessel stiffness (R-QVS) analysis and vector flow imaging (VFI). Methods: This prospective observational study included 347 pregnant women, comprising 108 normotensive controls and 239 women with GH. The GH group was further divided into normal-CIMT and increased-CIMT subgroups based on a mean CIMT threshold of 1.0 mm. All participants underwent standardized carotid ultrasonography. Stiffness-related parameters, including the hardness coefficient (HC) and pulse wave velocity (PWV), and flow-related parameters, including maximum wall shear stress (WSS Results: Carotid stiffness increased and wall shear stress (WSS) decreased progressively from the control group to the GH normal-CIMT and GH increased-CIMT groups. The GH increased-CIMT group had the highest PWV and the lowest WSS Conclusions: Women with GH exhibited a progressive high-stiffness and low-shear carotid phenotype, particularly in the presence of increased CIMT. Integrating R-QVS analysis and VFI may improve vascular risk stratification in hypertensive pregnancies.
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