Evidence map›Paper›PMID 42701368›Full record

ArticleInfection prevention in practice2026

Pharmacist-coordinated IDST treatment bundle achievement and impact on mortality in MRSA bacteraemia: a single-centre retrospective cohort study.

Aiju Endo, Yuki Hanai, Takahiro Mikawa, Daiki Asakawa, Taiki Ishibe, Yu Nakane, Misako Tanaka, Daichi Mitsui, Shinji Kido, Takeshi Nonaka and 10 more

Abstract read
In one paragraph

Article in Infection prevention in practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

20 authors.

Aiju EndoDepartment of Pharmacy, Yamanashi Prefectural Central Hospital, Kofu-city, Yamanashi, Japan.
Yuki HanaiLaboratory of Clinical Infectious Diseases and Therapeutics, Meiji Pharmaceutical University, Kiyose-city, Tokyo, Japan.
Takahiro MikawaDepartment of General Medicine and Infectious Diseases, Yamanashi Prefectural Central Hospital, Kofu-city, Yamanashi, Japan.
Daiki AsakawaDepartment of Pharmacy, Yamanashi Prefectural Central Hospital, Kofu-city, Yamanashi, Japan.
Taiki IshibeDepartment of Pharmacy, Yamanashi Prefectural Central Hospital, Kofu-city, Yamanashi, Japan.
Yu NakaneDepartment of Pharmacy, Yamanashi Prefectural Central Hospital, Kofu-city, Yamanashi, Japan.
Misako TanakaDepartment of General Medicine and Infectious Diseases, Yamanashi Prefectural Central Hospital, Kofu-city, Yamanashi, Japan.
Daichi MitsuiDepartment of General Medicine and Infectious Diseases, Yamanashi Prefectural Central Hospital, Kofu-city, Yamanashi, Japan.
Shinji KidoDepartment of General Medicine and Infectious Diseases, Yamanashi Prefectural Central Hospital, Kofu-city, Yamanashi, Japan.
Takeshi NonakaDepartment of General Medicine and Infectious Diseases, Yamanashi Prefectural Central Hospital, Kofu-city, Yamanashi, Japan.
Ken FujimoriDepartment of General Medicine and Infectious Diseases, Yamanashi Prefectural Central Hospital, Kofu-city, Yamanashi, Japan.
Nozomi KudoDepartment of General Medicine and Infectious Diseases, Yamanashi Prefectural Central Hospital, Kofu-city, Yamanashi, Japan.
Yuta NakadoiDepartment of General Medicine and Infectious Diseases, Yamanashi Prefectural Central Hospital, Kofu-city, Yamanashi, Japan.
Yukimasa KobayashiDepartment of General Medicine and Infectious Diseases, Yamanashi Prefectural Central Hospital, Kofu-city, Yamanashi, Japan.
Rintaro NegishiDepartment of General Medicine and Infectious Diseases, Yamanashi Prefectural Central Hospital, Kofu-city, Yamanashi, Japan.
Ayaka FujimoriDepartment of General Medicine and Infectious Diseases, Yamanashi Prefectural Central Hospital, Kofu-city, Yamanashi, Japan.
Mika TakatoriInfection Control Department, Yamanashi Prefectural Central Hospital, Kofu-city, Yamanashi, Japan.
Yasuyuki NatsumeInfection Control Department, Yamanashi Prefectural Central Hospital, Kofu-city, Yamanashi, Japan.
Kaori MatsumotoDepartment of Pharmacy, Yamanashi Prefectural Central Hospital, Kofu-city, Yamanashi, Japan.
Kazuaki MatsumotoDivision of Pharmacodynamics, Keio University Faculty of Pharmacy, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Methicillin-resistant Methods: We conducted a single-centre retrospective cohort study of adults with MRSA bacteraemia diagnosed between April 2020 and June 2025. Patients were categorized into IDST intervention or non-intervention groups. Bundle adherence (≥ 75% defined as ≥ 9/12 items) and 28- and 90-day mortality were analysed using Kaplan-Meier analysis with log-rank tests and Cox proportional-hazards models; two-sided Results: Eighty-five patients were included in the present study. Overall, bundle adherence ≥75% occurred in 57.6%; adherence was higher with IDST than without (79.5% vs 39.1%); 28-day mortality occurred in 26 (30.6%) and 90-day mortality in 42 (49.4%), respectively. Survival analysis showed lower 28-day (log-rank Conclusions: Pharmacist-coordinated IDST co-management significantly improved adherence to evidence-based care and was associated with reduced short- and intermediate-term mortality in patients with MRSA bacteraemia. This model may be applicable to hospitals with limited continuous on-site availability of infectious disease physicians, provided that specialist oversight remains accessible.

Indexed as

Antimicrobial stewardshipBundleInfectious disease supportMethicillin-resistant Staphylococcus aureus (MRSA) bloodstream infectionPharmacist-coordinatedQuality indicator (QI)

Identifiers

PMID42701368
PMCPMC13545305

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.