Evidence map›Paper›PMID 42700291›Full record

ArticleMedical oncology (Northwood, London, England)2026

CRC cell cycle arrest and early apoptosis induction by mononuclear octahedral cobalt(III) Schiff base through the inhibition of CDK4/6 and BCL2.

Abdolvahab Moshtaghian, Abasalt Hosseinzadeh Colagar, Ali Khaleghian, Tahereh Zahedi

Abstract read
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In one paragraph

Article in Medical oncology (Northwood, London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Abdolvahab MoshtaghianDepartment of Molecular and Cell Biology, Faculty of Basic Science, University of Mazandaran, Babolsar, Mazandaran, 47416-95447, Iran.
Abasalt Hosseinzadeh ColagarDepartment of Molecular and Cell Biology, Faculty of Basic Science, University of Mazandaran, Babolsar, Mazandaran, 47416-95447, Iran. acolagar@yahoo.com.
Ali KhaleghianNervous System Stem Cells Research Centre, Research Institute of Neuroscience, Semnan University of Medical Sciences, Semnan, Iran.
Tahereh ZahediDepartment of Marine Biology, Faculty of Marine Science and Technology, University of Hormozgan, Bandar Abbas, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Synthetic cobalt Schiff bases have recently emerged as promising metal-based anticancer candidates. In this study, we investigated the biological effects of a mononuclear octahedral cobalt(III) Schiff base complex [CoL

Indexed as

Antineoplastic AgentsApoptosisCell Cycle CheckpointsCobaltColorectal NeoplasmsCyclin-Dependent Kinase 4Cyclin-Dependent Kinase 6Proto-Oncogene Proteins c-bcl-2HT29 CellsHumansMolecular Docking SimulationSchiff BasesAntineoplastic AgentsBCL2 protein, humanCDK4 protein, humanCDK6 protein, humanCobaltCyclin-Dependent Kinase 4Cyclin-Dependent Kinase 6Proto-Oncogene Proteins c-bcl-2Schiff BasesApoptosisCDK4CDK6Cell cycleSynthetic cobalt Schiff base

Identifiers

PMID42700291

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.