Evidence map›Paper›PMID 42700169›Full record

ArticleJACC. Case reports2026

Progressive Giant Left Atrium After Valve Surgery With Preserved Hemodynamics.

Giulia Agostini, Marco Pocar, Matteo Marro, Luca Deorsola, Massimo Boffini, Antonino Loforte, Mauro Rinaldi

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Giulia AgostiniCardiac Surgery Division, Department of Surgical Sciences, City of Health and Science University Hospital, University of Turin, Turin, Italy. Electronic address: giulia.agostini@unito.it.
Marco PocarCardiac Surgery Division, Department of Surgical Sciences, City of Health and Science University Hospital, University of Turin, Turin, Italy.
Matteo MarroCardiac Surgery Division, Department of Surgical Sciences, City of Health and Science University Hospital, University of Turin, Turin, Italy.
Luca DeorsolaCardiac Surgery Division, Department of Surgical Sciences, City of Health and Science University Hospital, University of Turin, Turin, Italy.
Massimo BoffiniCardiac Surgery Division, Department of Surgical Sciences, City of Health and Science University Hospital, University of Turin, Turin, Italy.
Antonino LoforteCardiac Surgery Division, Department of Surgical Sciences, City of Health and Science University Hospital, University of Turin, Turin, Italy.
Mauro RinaldiCardiac Surgery Division, Department of Surgical Sciences, City of Health and Science University Hospital, University of Turin, Turin, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGiant left atrium (GLA) is a rare complication of rheumatic heart disease that may continue to enlarge despite successful valve surgery. CASE SUMMARY: A 69-year-old man with rheumatic valvular disease and previous mechanical mitral and aortic valve replacement developed progressive GLA and heart failure symptoms. Redo aortic valve replacement was performed for prosthetic dysfunction. Long-term follow-up demonstrated progressive atrial enlargement (indexed left atrial volume up to 1,172 mL/m DISCUSSION: GLA is typically associated with pulmonary hypertension and heart failure progression. This case is notable for extreme progressive atrial remodeling over 2 decades despite correction of the underlying valve disease, while preserving pulmonary hemodynamics and ventricular function. TAKE-HOME MESSAGES: Progressive GLA may remain compatible with prolonged survival after successful valve surgery when ventricular function and pulmonary hemodynamics are preserved. Long-term multimodality imaging and invasive hemodynamic assessment are essential for patient management.

Indexed as

atrial remodelingcardiac catheterizationgiant left atriumpulmonary hypertensionrheumatic heart disease

Identifiers

PMID42700169
PMCPMC13669898

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.