Evidence map›Paper›PMID 42700088›Full record

Trial reportMedicine2026

Effect of a modified soft contact lens combined with a noncontact wide-angle viewing system during vitrectomy.

Jintao Xia, Hongbing Zhang, Lina Cheng, Xiaogang Yang

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jintao XiaDepartment of Ophthalmology, First Affiliated Hospital of Northwest University, Xi'an No. 1 Hospital, Xi'an City, Shaanxi Province, China.
Hongbing ZhangDepartment of Ophthalmology, First Affiliated Hospital of Northwest University, Xi'an No. 1 Hospital, Xi'an City, Shaanxi Province, China.
Lina ChengDepartment of Ophthalmology, First Affiliated Hospital of Northwest University, Xi'an No. 1 Hospital, Xi'an City, Shaanxi Province, China.
Xiaogang YangDepartment of Ophthalmology, First Affiliated Hospital of Northwest University, Xi'an No. 1 Hospital, Xi'an City, Shaanxi Province, China.ORCID 0009-0009-3230-0204

Funding

Key Research and Development Program of Shaanxi Province 2024SF-YBXM-333
6 · The paper itself

Abstract

backgroundTo evaluate the efficacy of a modified soft contact lens (MSCL) in maintaining intraoperative visual clarity and protecting the cornea during vitrectomy using a noncontact wide-angle viewing system.

methodsPatients undergoing pars plana vitrectomy were randomly assigned to a balanced salt solution (BSS) group or an MSCL group. All surgeries were performed with a noncontact wide-angle viewing system. In the BSS group, the cornea was intermittently irrigated with BSS, whereas an MSCL was applied throughout surgery in the MSCL group. Surgical time, vitrectomy duration, intraoperative visual clarity, and frequency of corneal irrigation were recorded. Corneal epithelial edema, fluorescein staining, tear film breakup time, and central corneal thickness were assessed preoperatively and at 1 day, 1 week, and 1 month postoperatively. Ocular Surface Disease Index scores were evaluated preoperatively and at 1 month.

resultsThe MSCL group showed significantly better intraoperative visual clarity and corneal hydration than the BSS group (P < .05). Surgical time and vitrectomy duration were comparable between groups (P > .05). Corneal edema, fluorescein staining, and tear film breakup time at 1 day and 1 week were significantly improved in the MSCL group (P < .05), with no differences at 1 month. Ocular Surface Disease Index scores did not differ significantly between groups.

conclusionMSCL use effectively protects the cornea and improves intraoperative visualization during vitrectomy without adversely affecting postoperative ocular surface comfort.

Indexed as

Contact Lenses, HydrophilicVitrectomyAdultAgedCorneaFemaleHumansMaleMiddle Agednoncontact wide-angle viewing systemOcular Surface Disease Index (OSDI)soft contact lenssurgical fieldvitrectomy surgery

Identifiers

PMID42700088
PMCPMC13549601

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.