Evidence map›Paper›PMID 42700027›Full record

ArticleMedicine2026

High-grade B-cell lymphoma presenting with bulbar palsy and Tapia syndrome: A case report.

Han Luo, Zengxia Zhao, Bo Liu

Abstract readCase Reports
In one paragraph

Article in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Han LuoDepartment of Neurology, Shenzhen Longhua District Central Hospital, Shenzhen, Guangdong, China.ORCID 0009-0003-8619-3447
Zengxia Zhao

Funding

Key Medical Discipline Construction Fund of Shenzhen Longhua District 2025
6 · The paper itself

Abstract

rationaleBulbar palsy and Tapia syndrome (ipsilateral recurrent laryngeal and hypoglossal nerve palsy) are rarely the initial manifestations of lymphoma. Motor neuron disease is often the primary consideration in such cases, potentially leading to diagnostic delay. PATIENT CONCERNS: A 46-year-old male was admitted to the hospital on April 16, 2020, with the chief complaint of "dysphagia for 7 days." DIAGNOSIS: High-grade B-cell lymphoma.

interventionsThe patient received swallowing function rehabilitation training after admission. On May 12, 2020, a biopsy of a painful mass in the right mandibular area was performed. On May 20, 2020, systemic anti-tumor therapy was administered based on immunohistochemistry and FISH results. OUTCOMES: At the 2-month follow-up, the patient showed further weight loss, extensive extranodal and multi-organ involvement, indicating a poor prognosis. LESSONS: Lymphoma can present with isolated bulbar palsy and Tapia syndrome, mimicking motor neuron disease. Recognizing B symptoms and atypical neuroimaging findings is essential for early diagnosis. Furthermore, the etiology of carotid stenosis in lymphoma patients is often multifactorial, and treatment decisions must balance stroke prevention against bleeding and other tumor-related risks.

Indexed as

Bulbar Palsy, ProgressiveHypoglossal Nerve DiseasesLymphoma, B-CellVocal Cord ParalysisHumansMaleMiddle AgedSyndromeB symptomsbulbar palsycarotid artery stenosishigh-grade B-cell lymphomaTapia syndrome

Identifiers

PMID42700027
PMCPMC13549571

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.