Evidence map›Paper›PMID 42699989›Full record

ReviewActa paediatrica (Oslo, Norway : 1992)2026

Optimising Human Papillomavirus Vaccination Strategies for Faster Cervical Cancer Elimination.

Joakim Dillner

Abstract readReview
In one paragraph

Review in Acta paediatrica (Oslo, Norway : 1992), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Joakim DillnerDepartment of Clinical Sciences, Intervention & Technologies, Center for Cervical Cancer Elimination, Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0000-0001-8588-6506

Funding

Cancerfonden 201198PjF01HCancerfonden 201199UsF02HCenter for Innovative Medicine 20190809Center for Innovative Medicine 976207Swedish GovernmentVetenskapsrådet 2021-01228Vetenskapsrådet 2025-00252
6 · The paper itself

Abstract

aimCervical cancer elimination is a global public health goal, with vaccination against Human Papillomavirus (HPV) and HPV screening being two major prevention pillars. This review focuses on how vaccinations can be used in order to reach the timepoint of cervical cancer elimination faster.

methodsThe concepts in previously published reviews on 'faster cervical cancer elimination' are summarised and explained.

resultsMajor concepts explained are: HPV vaccines prevent not only cancer precursors, but also the HPV infection itself resulting in public health gains that exceed the individual direct vaccine protection because of herd immunity. The effective population coverages of vaccine-induced immunity required to reach the critical extinction level for infection elimination are moderate, in particular when gender-neutral vaccination is used. Major suggested enabling strategies include catch-up vaccinations of adolescents, one-dose HPV vaccination and use of HPV prevalences to monitor and optimise HPV vaccination programs. Finally, cervical screening with HPV testing is predicted to be easier if there are no new HPV infections.

conclusionThe major challenge for faster cervical cancer elimination is to design HPV vaccination strategies that achieve an effective population immunity against the HPV infection as fast as possible.

Indexed as

Human Papillomavirus VirusesPapillomavirus InfectionsPapillomavirus VaccinesUterine Cervical NeoplasmsFemaleHumansVaccinationPapillomavirus Vaccines

Identifiers

PMID42699989
PMCPMC13659424

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.