Evidence map›Paper›PMID 42699833›Full record

ReviewCureus2026

Preventable Factors in Fatal and Near-Fatal Asthma: Lessons From the British Thoracic Society (BTS) and the National Review of Asthma Deaths (NRAD).

Muhammad Meer, Mahnoor Mumtaz, Syed Zuhair, Nafiu Mukhtar

Abstract readReview
In one paragraph

Review in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Muhammad MeerAcute Medicine, Northampton General Hospital, Northampton, GBR.
Mahnoor MumtazInternal Medicine, King's College Hospital NHS Foundation Trust, London, GBR.
Syed ZuhairGeneral Medicine, Northampton General Hospital, Northampton, GBR.
Nafiu MukhtarAcute Medicine, Northampton General Hospital, Northampton, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Asthma is one of the most widespread chronic respiratory illnesses that is still a leading cause of high morbidity and mortality even in the context of effective therapies and evidence-based clinical practice. The British Thoracic Society (BTS)/Scottish Intercollegiate Guidelines Network (SIGN) provides a structured guideline on the management of asthma, and the National Review of Asthma Deaths (NRAD) has outlined the most significant gaps in routine asthma care that lead to preventable deaths. The purpose of the review is to consider the preventable aspects related to fatal and near-fatal asthma and to comment on the major learning points from the BTS/SIGN asthma guidelines and the results of the NRAD. A narrative database literature review was carried out using PubMed, Scopus, and Google Scholar to obtain relevant peer-reviewed literature published since 2005 till December 2025. Search words were fatal asthma, near-fatal asthma, asthma mortality, preventable factors, NRAD, and the BTS asthma guideline. Articles on asthma mortality, severe exacerbations, and asthma management using the guidelines were selected. The literature recognizes various preventable causes of fatal and near-fatal asthma; among them are poor adherence to inhaled corticosteroid treatment, overuse of short-acting β2-agonists (SABA), the presence of poor follow-up following an asthma attack, absence of individualized asthma action plans, and failure to recognize worsening symptoms. Findings in the NRAD research also indicated the shortcomings of standard check-ups of asthma, minimal use of controller drugs, and the inability to recognize at-risk patients as the key contributors to asthma death. It is possible to prevent many asthma deaths by increasing observance of guidelines, early recognition of high-risk patients, and providing them with more education and self-management support. Strengthening the implementation of the BTS/SIGN guidelines and addressing gaps in NRAD insights could be key to improving the quality of asthma care and preventing asthma-related deaths.

Indexed as

asthmaasthma deathsbts/sign guidelinesnear-fatal asthmanrad

Identifiers

PMID42699833
PMCPMC13544550

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.