ArticleBiochemistry and biophysics reports2026
Complex interactions between miR-107 and PTEN gene expression, more specifically in viral and NASH cirrhosis.
Article in Biochemistry and biophysics reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: microRNAs play critical roles in modulating the molecular pathways involved in liver fibrosis. miR-107 has been reported to be elevated in the liver of patients with non-alcoholic fatty liver disease (NAFLD), and it is believed to regulate the Methods: This case-control study assessed the gene expression levels using quantitative real-time PCR (qRT-PCR) in liver tissues from individuals with simple steatosis (n = 6), cirrhosis (n = 32), and histologically normal controls (n = 7). Results: miR-107 expression was significantly increased in cirrhotic tissues compared with controls (p < 0.05). The increase was mostly related to viral cirrhosis. Conclusion: These findings suggest that there are complex interactions between miR-107 and
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