Evidence map›Paper›PMID 42699722›Full record

ArticleiScience2026

Identification of elements determining

Hongchuan Li, Noah T Koenigs, Michael Ruesch, Ella Troy, Olivia Brancato-Buentello, Zhonghe Sun, Xiaolin Wu, Xiongfong Chen, Yongmei Zhao, Aharon G Freud and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hongchuan LiBasic Science Program, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.
Noah T KoenigsDepartment of Pathology, The Ohio State University, Columbus, OH 43210, USA.
Michael RueschComprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA.
Ella TroyDepartment of Pathology, The Ohio State University, Columbus, OH 43210, USA.
Olivia Brancato-BuentelloComprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA.
Zhonghe SunFrederick Sequencing and Genomics Core, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.
Xiaolin WuFrederick Sequencing and Genomics Core, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.
Xiongfong ChenFrederick Sequencing and Genomics Core Bioinformatics Group, Advanced Biomedical and Computational Science, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.
Yongmei ZhaoFrederick Sequencing and Genomics Core Bioinformatics Group, Advanced Biomedical and Computational Science, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.
Aharon G FreudDepartment of Pathology, The Ohio State University, Columbus, OH 43210, USA.
Stephen K AndersonBasic Science Program, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.

Funding

WORK ORDER 126643 B539 EXPAND IC SUITE75N91019D00024 · NIAID · LEIDOS BIOMEDICAL RESEARCH, INC. · PI BRISCOE, LYNN · 2019 to 2025
$3932.6M
Elucidation of Human Natural Killer Cell DevelopmentR01CA208353 · NCI · OHIO STATE UNIVERSITY · PI AHARON G FREUD · 2017 to 2026
$4.0M
Mechanistic regulation of HLA binding receptors during human natural killer cell developmentR01AI198432 · NIAID · OHIO STATE UNIVERSITY · PI AHARON G FREUD · 2026 to 2026
$693k
NCI NIH HHS R01 CA208353NIAID NIH HHS R01 AI198432NIH HHS 75N91019D00024
6 · The paper itself

Abstract

The variegated expression of the KIR family of class I MHC receptors generates specialized natural killer (NK) cells capable of allele-specific

Indexed as

6-base sequencingepigenetic regulationhumanhydroxymethylcytosineKIRNK cellsTET2

Identifiers

PMID42699722
PMCPMC13544304

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.