Evidence map›Paper›PMID 42699553›Full record

ArticleBrain communications2026

Prion protein (PrP) profiles in blood and CSF: insights into pre-symptomatic and symptomatic prion disease.

Inês Laginha, Matthias Schmitz, Ângela da Silva Correia, Tayyaba Saleem, Susana da Silva Correia, Saima Zafar, Neelam Younas, Sezgi Canaslan, Stefan Göbel, Elisabeth Root and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Inês LaginhaNational Reference Center for CJD Surveillance, Department of Neurology, University Medical Center, 37075 Göttingen, Germany.
Matthias SchmitzNational Reference Center for CJD Surveillance, Department of Neurology, University Medical Center, 37075 Göttingen, Germany.ORCID https://orcid.org/0000-0002-5502-681X
Ângela da Silva CorreiaNational Reference Center for CJD Surveillance, Department of Neurology, University Medical Center, 37075 Göttingen, Germany.
Tayyaba SaleemNational Reference Center for CJD Surveillance, Department of Neurology, University Medical Center, 37075 Göttingen, Germany.
Susana da Silva CorreiaNational Reference Center for CJD Surveillance, Department of Neurology, University Medical Center, 37075 Göttingen, Germany.
Saima ZafarNational Reference Center for CJD Surveillance, Department of Neurology, University Medical Center, 37075 Göttingen, Germany.ORCID https://orcid.org/0000-0002-4261-0339
Neelam YounasNational Reference Center for CJD Surveillance, Department of Neurology, University Medical Center, 37075 Göttingen, Germany.
Sezgi CanaslanNational Reference Center for CJD Surveillance, Department of Neurology, University Medical Center, 37075 Göttingen, Germany.
Stefan GöbelNational Reference Center for CJD Surveillance, Department of Neurology, University Medical Center, 37075 Göttingen, Germany.
Elisabeth RootNational Reference Center for CJD Surveillance, Department of Neurology, University Medical Center, 37075 Göttingen, Germany.
Maren BreitbarthNational Reference Center for CJD Surveillance, Department of Neurology, University Medical Center, 37075 Göttingen, Germany.
Anna-Lisa FischerNational Reference Center for CJD Surveillance, Department of Neurology, University Medical Center, 37075 Göttingen, Germany.
Kathrin DittmarNational Reference Center for CJD Surveillance, Department of Neurology, University Medical Center, 37075 Göttingen, Germany.
Dana ŽakovaNational Reference Center for Prion Diseases and Slow Viral Infections, Slovak Medical University, 833 03 Bratislava, Slovakia.
Peter HermannNational Reference Center for CJD Surveillance, Department of Neurology, University Medical Center, 37075 Göttingen, Germany.
Inga ZerrNational Reference Center for CJD Surveillance, Department of Neurology, University Medical Center, 37075 Göttingen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The conversion of native prion protein (PrP) into its misfolded isoform, scrapie (PrP

Indexed as

cerebrospinal fluidfatal familial insomniaplasmaprion diseasePrP

Identifiers

PMID42699553
PMCPMC13543685

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.