Evidence map›Paper›PMID 42699418›Full record

ArticleJournal of public health in Africa2026

Admission haemoglobin and albumin as correlates of central nervous system inflammation in

Westain T Nyirenda, Lovemore Mapahla, Bonheur Dounebaine, Nebiyu Dereje, Peter S Nyasulu

Abstract read
In one paragraph

Article in Journal of public health in Africa, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Westain T NyirendaDivision of Epidemiology and Biostatistics, Department of Global Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.ORCID https://orcid.org/0009-0006-5821-3844
Lovemore MapahlaDivision of Epidemiology and Biostatistics, Department of Global Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.ORCID https://orcid.org/0000-0002-0146-3299
Bonheur DounebaineAfrica Centres for Disease Control and Prevention, Addis Ababa, Ethiopia.ORCID https://orcid.org/0000-0002-9303-9320
Nebiyu DerejeAfrica Centres for Disease Control and Prevention, Addis Ababa, Ethiopia.ORCID https://orcid.org/0000-0001-5406-4171
Peter S NyasuluDivision of Epidemiology and Biostatistics, Department of Global Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.ORCID https://orcid.org/0000-0003-2757-0663

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Aim: This study aimed to evaluate routine admission clinical and laboratory measures as correlates of cerebrospinal-fluid white-cell count and to describe changes in this count during early hospital care. Setting: The study was conducted at Rumphi District Hospital, a public secondary-level treatment facility serving rural communities in the Vwaza Marsh focus of northern Malawi. Methods: We retrospectively studied patients aged ≥ 6 years with parasitological confirmed Results: Forty-three patients met the eligibility criteria; 43 contributed admission counts, and 42 contributed Day-11 counts. Day-11 cerebrospinal-fluid white-cell counts were 75% lower than admission counts (aIRR = 0.25, 95% CI: 0.14-0.45; Conclusion: Lower haemoglobin and albumin were associated with greater cerebrospinal-fluid inflammation, which declined during early care. As accessible admission measures, they may support recognition, triage and monitoring of CNS burden in Contribution: This study links routine blood measures to cerebrospinal-fluid inflammation in

Indexed as

Albumincentral nervous system involvementcerebrospinal fluid white-cell counthaemoglobinrhodesiense human African trypanosomiasissleeping sickness

Identifiers

PMID42699418
PMCPMC13543251

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.