Evidence map›Paper›PMID 42699260›Full record

ArticleJHLT open2026

Cold ischemic time and early vasoactive-inotropic support following heart transplantation with HTK-preserved donor hearts.

Truc Mai Nguyen, Zied Ltaief, Filip Dulguerov, Tamila Abdurashidova, Anna Nowacka, Valentina Rancati, Philippe Meyer, Léa Iten, Olivier Muller, Patrick Yerly and 3 more

Abstract read
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In one paragraph

Article in JHLT open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Truc Mai NguyenDivision of Cardiology, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.
Zied LtaiefDepartment of Adult Intensive Care Medicine, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.
Filip DulguerovDivision of Cardiac Surgery, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.
Tamila AbdurashidovaDivision of Cardiac Surgery, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.
Anna NowackaDivision of Cardiac Surgery, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.
Valentina RancatiDivision of Anesthesiology, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.
Philippe MeyerDivision of Cardiology, Geneva University Hospital, University of Geneva, Geneva, Switzerland.
Léa ItenDivision of Cardiology, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.
Olivier MullerDivision of Cardiology, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.
Patrick YerlyDivision of Cardiology, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.
Roger HullinDivision of Cardiology, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.
Matthias KirschDivision of Cardiac Surgery, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.
Henri LuDivision of Cardiology, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Whether longer cold ischemic time (CIT) increases early hemodynamic support after heart transplantation (HTx) with histidine-tryptophan-ketoglutarate (HTK) preservation is unclear. We examined the association between CIT and the vasoactive-inotropic score (VIS), a marker of circulatory support. We studied consecutive adults transplanted with HTK-preserved grafts at Lausanne University Hospital (January 2016-March 2025). VIS was calculated hourly for 48 h after ICU admission, and its association with CIT modeled using restricted cubic splines. Among 130 recipients (75% male, aged 52±12 years), mean CIT was 152±50 min. Longer CIT was associated with higher 24-hour VIS (P

Indexed as

cold ischemic timegraft preservationheart transplantationischemia-reperfusion injuryvasoactive-inotropic score

Identifiers

PMID42699260
PMCPMC13544163

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.