Evidence map›Paper›PMID 42699253›Full record

ReviewFrontiers in immunology2026

Myeloid-associated B-cell identity remodeling in CAR T-cell resistance: a hypothesis-generating framework for diffuse large B-cell lymphoma.

Gaojie Liu, Junwei Yang, Han Li, Jingyi Bao, Liuxin Jiang, Lishuo Deng, Yuetong Tan, Yuxiang Song, Yao Wang

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Gaojie Liu *Department of Gastrointestinal Surgery, The Affiliated Cancer Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China.
Junwei Yang *Guangzhou Institute of Cancer Research, The Affiliated Cancer Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China.
Han Li *Guangzhou Institute of Cancer Research, The Affiliated Cancer Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China.
Jingyi BaoGuangzhou Institute of Cancer Research, The Affiliated Cancer Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China.
Liuxin JiangGuangzhou Institute of Cancer Research, The Affiliated Cancer Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China.
Lishuo DengGuangzhou Institute of Cancer Research, The Affiliated Cancer Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China.
Yuetong TanGuangzhou Institute of Cancer Research, The Affiliated Cancer Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China.
Yuxiang SongCollege of Mathematics and Statistics, Hubei Normal University, Huangshi, Hubei, China.
Yao WangDepartment of Medical Oncology, The Affiliated Cancer Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CD19-directed chimeric antigen receptor (CAR) T-cell therapy has transformed the treatment of relapsed or refractory large B-cell lymphoma (LBCL), including diffuse large B-cell lymphoma (DLBCL), yet primary resistance and relapse remain frequent. Clinical studies link pretreatment B-cell gene expression signatures,

Indexed as

B-LymphocytesImmunotherapy, AdoptiveLymphoma, Large B-Cell, DiffuseMyeloid CellsReceptors, Chimeric AntigenAnimalsAntigens, CD19HumansTumor MicroenvironmentAntigens, CD19Receptors, Chimeric Antigenantigen escapeB-cell identityCAR T-cell resistanceCD19diffuse large B-cell lymphomalarge B-cell lymphomamyeloid cellstumor microenvironment

Identifiers

PMID42699253
PMCPMC13542975

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.