ArticleCureus2026
Comparative Evaluation of the Push-Out Bond Strength and Antimicrobial Efficacy of Biodentine and Bioactive Bone Cement as Root-End Filling Materials: An In Vitro Study.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
2 authors.
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Abstract
introductionThe long-term success of endodontic microsurgery depends on the use of root-end filling materials that provide effective apical sealing while preventing microbial leakage. An ideal retrograde filling material should possess excellent bond strength, biocompatibility, and antimicrobial properties. Biodentine has demonstrated favorable biological and mechanical properties. However, modified bioactive bone cement incorporating mineral trioxide aggregate (MTA) and gentamicin may offer enhanced antibacterial performance. This study compared the push-out bond strength and antimicrobial efficacy of Biodentine and modified bioactive bone cement as root-end filling materials. MATERIALS AND
methodsThis in vitro experimental study included 60 extracted human mandibular premolars, which were randomly allocated into two groups (n=30): Biodentine and modified bioactive bone cement. Standardized root-end cavity preparation was performed following canal instrumentation and obturation. Push-out bond strength was evaluated using a universal testing machine, while antimicrobial efficacy against
resultsBiodentine demonstrated significantly greater push-out bond strength than modified bioactive bone cement (p<0.001). Conversely, modified bioactive bone cement exhibited significantly greater antimicrobial efficacy against
conclusionUnder the conditions of this in vitro study, Biodentine demonstrated significantly greater push-out bond strength, whereas modified bioactive bone cement exhibited significantly greater antimicrobial activity against
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