Observational studyDepression and anxiety2026
Sensory Processing Profiles in Depression: Evidence of Dynamic Changes and Clinical Correlates Over 3 Months.
Observational study in Depression and anxiety, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Sensory processing difficulties are increasingly recognized in major depressive disorder (MDD), with patients often exhibiting heightened sensitivity, avoidance, and low registration. However, the temporal stability of these patterns-trait vs. state-remains unclear. Methods: In this longitudinal study, 45 adult inpatients with MDD were assessed using the Adolescent/Adult Sensory Profile (AASP) at admission and 3 months later; 34 completed both assessments. Clinical variables included depression (Hamilton Depression Rating Scale [HDRS-17]), anxiety (Hamilton Anxiety Rating Scale [HARS]), anhedonia (Snaith-Hamilton Pleasure Scale [SHAPS]), self-esteem (Rosenberg Self-Esteem Inventory [RSEI]), and psychomotor retardation (Clinical Outcomes in Routine Evaluation [CORE]). Nonparametric tests examined sensory changes and associations with clinical outcomes. Results: At follow-up, 61.8% of participants showed clinical improvement and 44.1% achieved remission. Significant decreases in low registration and sensory sensitivity, along with increased sensation seeking, indicated that sensory processing is dynamic and partially state-dependent. Sensory avoidance remained stable and was more pronounced in recurrent MDD. Patients with clinical improvement or remission had sensory profiles closer to normative ranges. Higher sensitivity and avoidance correlated with more severe depression, anxiety, and lower self-esteem, while greater sensation seeking was associated with better outcomes. Conclusions: Sensory processing profiles in MDD are state-dependent and linked to clinical changes. These findings support the relevance of sensory traits as potential clinical markers and therapeutic targets. Personalized interventions addressing sensory processing may contribute to improved treatment outcomes. Further longitudinal and multimodal research is needed to clarify their predictive value.
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