Evidence map›Paper›PMID 42698761›Full record

ArticleJournal of traditional and complementary medicine2026

Ethyl acetate fraction of

Eun-Young Kim, Myunghyun Kim, Yujin Lee, Donghyun Kang, Dohun Kwon, Youngjoo Sohn, Hyuk-Sang Jung

Abstract read
In one paragraph

Article in Journal of traditional and complementary medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Eun-Young KimDepartment of Anatomy, College of Korean Medicine, Kyung Hee University, Seoul, 02447, Republic of Korea.
Myunghyun KimDepartment of Anatomy, College of Korean Medicine, Kyung Hee University, Seoul, 02447, Republic of Korea.
Yujin LeeDepartment of Anatomy, College of Korean Medicine, Kyung Hee University, Seoul, 02447, Republic of Korea.
Donghyun KangDepartment of Anatomy, College of Korean Medicine, Kyung Hee University, Seoul, 02447, Republic of Korea.
Dohun KwonDepartment of Anatomy, College of Korean Medicine, Kyung Hee University, Seoul, 02447, Republic of Korea.
Youngjoo SohnDepartment of Anatomy, College of Korean Medicine, Kyung Hee University, Seoul, 02447, Republic of Korea.
Hyuk-Sang JungDepartment of Anatomy, College of Korean Medicine, Kyung Hee University, Seoul, 02447, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aim: Experimental procedure: To investigate the effect of the ADN-ethyl acetate (ADN-EA) extract, cells were pre-treated with ADN-EA, after which HaCaT cells were stimulated with TNF-α/IFN-γ, HMC-1 cells with PMA and A23187, and RPMCs with compound 48/80. Cytokine levels were analyzed with ELISA and PCR. ADN-EA efficacy in the DNCB-AD model was assessed by SCORAD, scratching behavior, IgE and cytokine levels in blood, and inflammatory cell infiltration in skin lesions using histology and immunohistochemistry. Effects of ADN-EA on the MAPK and STAT pathways in skin lesions were analyzed by western blotting. Results: Conclusion: These results indicate that ADN-EA may alleviate allergic inflammation by modulating the MAPK and STAT1 signaling pathways, suggesting its potential as a therapeutic option for managing AD.

Indexed as

Abeliophyllum distichum NakaiAtopic dermatitisHaCaT cellsHMC-1 cellsInflammation

Identifiers

PMID42698761
PMCPMC13541771

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.