ArticleFrontiers in neuroscience2026
Brain dynamic audio stimulation for subjective sleep disturbances in healthcare professionals: a single-arm pilot feasibility study.
Article in Frontiers in neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Insomnia and sleep disturbances are highly prevalent among healthcare professionals and pose risks to patient safety. Brain Dynamic Audio Stimulation (BDAS) is a non-invasive, open-loop auditory intervention intended to facilitate sleep initiation. This single-arm pilot feasibility study examined the feasibility and preliminary signal of a 14-day BDAS intervention in healthcare professionals with subjective sleep disturbances. Methods: Of 30 healthcare professionals assessed for eligibility, 15 were enrolled. Participants received one 30-min BDAS session nightly for 14 consecutive days. Insomnia severity was assessed using the Insomnia Severity Index (ISI) at baseline and Day 14. Short-duration EEG recordings (30 min, time-locked to BDAS, focused on sleep initiation) were obtained at both time points. Pre-post changes were analyzed using paired-sample tests; EEG outcomes were considered exploratory. Results: All 15 participants completed the intervention (100% retention; no adverse events). Mean ISI scores decreased from 10.00 (SD 5.55) to 4.27 (SD 2.69) (mean change -5.73; 95% CI - 8.15 to -3.32; Cohen's Conclusion: BDAS demonstrated feasibility and acceptability in a healthcare professional setting. The observed within-participant improvements in insomnia severity and exploratory EEG parameters provide a preliminary signal and effect size estimates to inform future randomized controlled trials. Because the design was single-arm and uncontrolled, these within-participant changes cannot be attributed to BDAS specifically.
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