Evidence map›Paper›PMID 42698600›Full record

ArticleFrontiers in cellular and infection microbiology2026

Integrated microbial and transcriptomic profiling reveals distinct correlations in atrophic gastritis associated with liver cirrhosis.

Yiqing Zhu, Guoming Zhang, Ruiguang Ma, Qian Li, Huayu Dai, Zhouyue Li, Lixiang Li, Zhen Li

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Yiqing Zhu *Department of Gastroenterology, Qilu Hospital of Shandong University, Jinan, Shandong, China.
Guoming Zhang *Department of Gastroenterology, Qilu Hospital of Shandong University, Jinan, Shandong, China.
Ruiguang MaDepartment of Gastroenterology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Qian LiDepartment of Gastroenterology, Binzhou Medical University Hospital, Binzhou, Shandong, China.
Huayu DaiDepartment of Gastroenterology, Qilu Hospital of Shandong University, Jinan, Shandong, China.
Zhouyue LiDepartment of Gastroenterology, Qilu Hospital of Shandong University, Jinan, Shandong, China.
Lixiang LiDepartment of Gastroenterology, Qilu Hospital of Shandong University, Jinan, Shandong, China.
Zhen LiDepartment of Gastroenterology, Qilu Hospital of Shandong University, Jinan, Shandong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To explore the alterations in the microbiota and transcriptome of patients with chronic atrophic gastritis (CAG) and liver cirrhosis (LC) and to develop robust diagnostic models. Methods: 16S ribosomal RNA (rRNA) amplicon sequencing was performed on saliva and gastric mucosal samples, and transcriptome sequencing was performed on gastric mucosal samples from the study participants. Results: Conclusion: LC is associated with distinct microbial and transcriptomic reprogramming in CAG, with enrichment of the PI3K-Akt signaling and bile secretion pathways, suggesting their possible involvement in cirrhosis-associated gastric mucosal changes and warranting further investigation.

Indexed as

BacteriaGastritis, AtrophicGene Expression ProfilingLiver CirrhosisMicrobiotaTranscriptomeFemaleGastric MucosaHumansMaleMiddle AgedRNA, Ribosomal, 16SRNA, Ribosomal, 16Schronic atrophic gastritisliver cirrhosismachine learningmicrobiotatranscriptome

Identifiers

PMID42698600
PMCPMC13541563

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.