ArticleFrontiers in medicine2026
Early-stage IgM kappa proliferative glomerulonephritis with monoclonal immunoglobulin deposition presenting with atypical renal insufficiency: a case report and literature review.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Proliferative glomerulonephritis with monoclonal immunoglobulin deposits (PGNMID) is a rare subtype of monoclonal gammopathy of renal significance (MGRS). While the IgG subtype has been well characterized, the IgM- Patient concerns and diagnoses: A 70-year-old male presented with incidentally detected microscopic hematuria and elevated serum creatinine, without overt edema, gross hematuria or systemic symptoms. Renal biopsy demonstrated a membranoproliferative pattern of glomerular injury, with monoclonal IgM deposition showing kappa light chain restriction and negative C3 staining, confirming the diagnosis of PGNMID. Bone marrow biopsy revealed no clonal lymphoplasmacytic proliferation, consistent with MGRS. The patient's serum creatinine level remained stable with a slight decrease from the baseline value, and the urinary red blood cell count returned to normal. Outcomes: After 7 months of follow-up, the patient's serum creatinine levels remained stable with a mild decrease from baseline. This case indicates that IgM-
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.