Evidence map›Paper›PMID 42698406›Full record

ArticleFrontiers in surgery2026

Association of labor epidural analgesia with early postpartum pelvic floor function in primiparous women undergoing vaginal delivery: a retrospective cohort study.

Lishan Lin, Yidan Wang, Yaping Wang, Mengjie Yan, Mingting Wang, Suoqin Ge, Junsheng Zhu, Maohong Gu

Abstract read
In one paragraph

Article in Frontiers in surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Lishan Lin *Department of Obstetrics and Gynecology, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, China.
Yidan Wang *Department of Ultrasound, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, China.
Yaping WangDepartment of Obstetrics and Gynecology, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, China.
Mengjie YanDepartment of Obstetrics and Gynecology, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, China.
Mingting WangDepartment of Obstetrics and Gynecology, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, China.
Suoqin GeDepartment of Obstetrics and Gynecology, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, China.
Junsheng ZhuDepartment of Anesthesiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, China.
Maohong GuDepartment of Obstetrics and Gynecology, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The association between labor epidural analgesia (LEA) and postpartum pelvic floor function remains uncertain. We evaluated whether LEA was associated with pelvic floor outcomes in primiparous women undergoing vaginal delivery. Methods: This single-center retrospective cohort study included 200 primiparous women with singleton, cephalic vaginal deliveries. Participants were classified according to LEA exposure. Baseline and peripartum characteristics were compared in the overall cohort. Early postpartum pelvic floor outcomes at 6-8 weeks were analyzed in 191 women, and multivariable regression was performed in 175 complete cases. Outcomes included type I and type II pelvic floor surface electromyography, bladder neck mobility, posterior bladder angle during Valsalva, levator hiatus area during Valsalva, urinary incontinence, and pelvic organ prolapse. The multivariable models additionally adjusted for second-stage labor duration and oxytocin use, which were considered potential labor-process variables in the interpretation of the adjusted estimates. Results: No statistically significant differences were identified in the measured baseline characteristics between the LEA and non-LEA groups. Compared with non-LEA, LEA was associated with longer first-, second-, and third-stage labor, longer total labor duration, and more frequent oxytocin use. No significant detectable between-group differences were observed in any pelvic floor parameter, urinary incontinence, pelvic organ prolapse, prolapse stage, or levator avulsion. After adjustment for maternal age, pre-pregnancy body mass index, gestational age, neonatal birth weight, second-stage labor duration, and oxytocin use, LEA was not significantly associated with any continuous pelvic floor outcome, urinary incontinence (adjusted odds ratio, 1.305; 95% confidence interval, 0.629-2.710), or pelvic organ prolapse (1.771; 0.717-4.373). Conclusions: LEA was associated with altered labor characteristics, whereas no statistically detectable association with worse pelvic floor outcomes at 6-8 weeks postpartum was observed after adjustment for the measured covariates. Given the observational design, potential residual confounding, and limited precision for infrequent outcomes, modest associations cannot be excluded.

Indexed as

labor epidural analgesiapelvic floor functionpostpartum recoveryprimiparous womenvaginal delivery

Identifiers

PMID42698406
PMCPMC13541434

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.