ArticleCancer imaging : the official publication of the International Cancer Imaging Society2026
Machine learning based on preoperative CT for noninvasive prediction of recurrence-free survival in gastrointestinal stromal tumors.
Article in Cancer imaging : the official publication of the International Cancer Imaging Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveClinicians need a reliable, noninvasive tool that can predict the risk of gastrointestinal stromal tumor (GIST) recurrence preoperatively. We aimed to develop a machine learning model based on preoperative contrast-enhanced CT (CECT) to predict recurrence-free survival (RFS) in GIST patients who underwent radical resection. MATERIALS AND
methodsA total of 192 patients with intermediate- and high-risk GISTs who underwent radical resection and subsequently received adjuvant imatinib were included, with a minimum follow-up duration of 24 months. A machine learning model (Model
resultsThe C-index values of the Model
conclusionWe found the machine learning-based preoperative CECT performed better than the AFIP index in prediction of RFS of GIST patients, especially at the 5th year, predicting recurrence risk in patients who underwent radical resection and receiving adjuvant therapy. This model may serve as a non-invasive tool to identify high-risk individuals who require more intensive surveillance and personalized management following radical resection.
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