Evidence map›Paper›PMID 42698074›Full record

Trial reportBMC oral health2026

Evaluation of postoperative pain associated with different working length determination methods: a randomised clinical study.

Gamze Nalci Calik, Betül Aycan Alim Uysal, Fatma Begüm Peker, Mehmet Burak Guneser

Registry-linked trialAbstract readRandomized Controlled TrialComparative Study
In one paragraph

Trial report in BMC oral health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07271797 (Comparing Different Electronic Apex Locators and Periapical Radiography on Postoperative Pain), which is not on this map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07271797 nacompletednot on this map

Comparing Different Electronic Apex Locators and Periapical Radiography on Postoperative Pain: A Randomized Clinical Study

TypeinterventionalSponsorBezmialem Vakif UniversityRan2023 to 2025Enrolled125ConditionsPostoperative Acute PainArmsRoot ZX (Morita Corp., Tokyo, Japan), Propex Pixi (Dentsply Maillefer, Ballaigues, Switzerland), Woodpex III (Woodpecker Medical Instrument Co., Guilin, China), Raypex 6 (VDW, Munich, Germany), periapical radiography
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gamze Nalci CalikDepartment of Endodontics, Bezmialem Vakif University, Faculty of Dentistry, Istanbul, Türkiye. nalcigamze@gmail.com.
Betül Aycan Alim UysalDepartment of Endodontics, Health Science University, Faculty of Dentistry, Istanbul, Türkiye.
Fatma Begüm PekerDepartment of Endodontics, Bezmialem Vakif University, Faculty of Dentistry, Istanbul, Türkiye.
Mehmet Burak GuneserDepartment of Endodontics, Bezmialem Vakif University, Faculty of Dentistry, Istanbul, Türkiye.

Funding

Bezmialem Vakıf Üniversitesi 20210816
6 · The paper itself

Abstract

backgroundPostoperative pain is a common concern in endodontic treatment. In teeth with asymptomatic irreversible pulpitis, accurate working length determination is critical for effective root canal therapy and may influence postoperative discomfort. This study compared postoperative pain following root canal treatment in teeth with asymptomatic irreversible pulpitis when working length was determined using one of four electronic apex locators or periapical radiography.

methodsA total of 125 patients with asymptomatic irreversible pulpitis in single-rooted, single-canal teeth were included in the analysis. Patients were randomly assigned to five groups according to the working length determination method: Root ZX, Propex Pixi, Woodpex III, Raypex 6, or periapical radiography. A single clinician performed standardised root canal treatment in a single visit. Pain was assessed using the visual analogue scale at 6, 12, 24, and 48 hours postoperatively, and analgesic intake was recorded.

resultsPostoperative pain gradually decreased over time in all groups. No statistically significant differences in postoperative pain were observed among the five working length determination methods at any postoperative assessment time point (all P > 0.05). Furthermore, postoperative pain was not significantly associated with age, sex, tooth location, and analgesic intake did not differ significantly among the groups.

conclusionUnder the standardised clinical conditions of this randomised clinical trial, the method used for working length determination did not significantly influence postoperative pain after single-visit root canal treatment in patients with asymptomatic irreversible pulpitis.

trial registrationThis study was retrospectively registered at ClinicalTrials.gov (Identifier: NCT07271797) on November 16, 2025. However, the study protocol, eligibility criteria, primary and secondary outcome measures, and statistical analysis plan were established before patient enrolment.

Indexed as

OdontometryPostoperative PainPulpitisRoot Canal TherapyAdultFemaleHumansMaleMiddle AgedPain MeasurementTooth ApexElectronic apex locatorPostoperative painRoot canal therapyWorking length

Identifiers

PMID42698074
PMCPMC13543454

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.