ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2026
Post-diagnosis cannabis use and its association with health status and quality of life in cancer survivors.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeTo examine whether measures of health status and quality of life (QoL) were associated with cannabis use after cancer diagnosis.
methodsIndividuals who received care at an NCI-designated cancer center from 2018 to 2019 (n = 5,901) were invited to complete an online survey in 2022, of which 954 responded. We included 652 respondents in this study, which were weighted to represent the cancer center patient population [58.6% non-Hispanic White; 58.5% female; 51.8% ≥ 65 years]. We examined three self-rated exposures including physical health, mental health, and QoL each assessed using a single survey item with response options ranging from poor to excellent and dichotomized as 'Average or Below Average' or 'Above Average' (referent). Post-diagnosis cannabis use was self-reported as 'Yes' or 'No' (referent). Survey-weighted logistic regression was used to estimate adjusted odds ratios (ORs) and 95% confidence intervals (CIs), and to explore whether these associations differed by cancer stage, treatment status, or pre-diagnosis cannabis use.
resultsMost reported above average status for mental health (67.2%) and QoL (64.2%), and almost half (47.1%) reported above average physical health. Odds of post-diagnosis cannabis use were significantly higher among survivors with average or below average mental health (OR = 1.88; 95%CI = 1.13-3.11). Associations were positive but not statistically significant for physical health (OR = 1.38; 95%CI = 0.85-2.24) and QoL (OR = 1.24; 95%CI = 0.75-2.05). These associations did not significantly differ by cancer stage, treatment status, or pre-diagnosis cannabis use.
conclusionCancer survivors reporting average or below average health status or QoL had higher odds of cannabis use.
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