Evidence map›Paper›PMID 42697374›Full record

ArticleMolecular metabolism2026

Transition to dietary plant-based proteins requires functional liver GDH for proper control of ammonia and energy homeostasis.

Yan Zhou, Angela M Ramos-Lobo, Tingting Fu, Hector Gallart-Ayala, Julijana Ivanisevic, Pierre Maechler

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular metabolism, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yan ZhouDepartment of Cell Physiology and Metabolism, University of Geneva Medical School, Geneva, Switzerland.
Angela M Ramos-LoboDepartment of Cell Physiology and Metabolism, University of Geneva Medical School, Geneva, Switzerland.
Tingting FuDepartment of Quantum Matter Physics, Laboratory of Advanced Technology, University of Geneva, Geneva, Switzerland.
Hector Gallart-AyalaMetabolomics Platform, University of Lausanne, Lausanne, Switzerland.
Julijana IvanisevicMetabolomics Platform, University of Lausanne, Lausanne, Switzerland.
Pierre MaechlerDepartment of Cell Physiology and Metabolism, University of Geneva Medical School, Geneva, Switzerland. Electronic address: pierre.maechler@unige.ch.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plant-based diet is growingly recommended, although switching the source of proteins from animal to plant regimen requires metabolic adaptations. According to its pivotal function in bridging amino acids and glucose homeostasis, we investigated the role of liver GDH in short-term adaptation to plant versus animal dietary proteins keeping the same spectrum of macronutrients. Control and Hep-Glud1

Indexed as

Dietary proteinsGluconeogenesisGlutamate dehydrogenaseLiver

Identifiers

PMID42697374
PMCPMC13594857

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.