ArticleJornal brasileiro de nefrologia
Living kidney donation in Brazil, 2010-2023: a descriptive time-series analysis.
Article in Jornal brasileiro de nefrologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
introductionChronic kidney disease imposes a high clinical and economic burden on the Brazilian Unified Health System, and kidney transplantation represents one of the best therapeutic choices for selected patients.
objectiveTo describe trends in living-donor (LD) kidney transplantation in Brazil (2010-2023), analyzing the donor-recipient relationship and the operational stock-to-annual production ratio on the waiting list, as well as to compare hospital indicators and estimated patient and graft survival between LD and deceased-donor (DD) kidney transplants.
methodsThis descriptive time-series study used aggregated, publicly available data.
resultsThe waiting list increased by 15% (from 33,253 to 38,258), and the total number of transplants rose by 29% (from 4,656 to 6,047). Data showed an increase in deceased-donor transplants (from 3,001 to 5,189) and a decrease in LD transplants (from 1,655 to 858), with the LD share declining from 35.55% to 14.19% and the per-million-population rate falling from 8.8 to 4.2. Among LD, there was a relative decrease in related donors (from 82.80% to 71.21%), a relative increase in unrelated spouse donors (from 10.57% to 18.65%), and a relative increase in other unrelated donors (from 6.64% to 10.14%). In descriptive comparisons, LD transplantation showed higher published patient and graft survival estimates and more favorable hospital indicators, including lower in-hospital mortality, shorter length of stay, and lower mean hospital admission authorization values.
conclusionThe findings suggest the relevance of integrated strategies to sustain deceased-donor procurement and strengthen living-donor kidney transplantation. However, comparisons between donor types were descriptive and should not be interpreted as causal.
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