Evidence map›Paper›PMID 42696584›Full record

ArticleScience advances2026

Glucose-TOR-PDCB signaling restricts cell-to-cell communication through callose deposition.

Michael Busche, Anne M Runkel, Min Xu, Katherine A Klimpel, Sannidhi Menon, Katherine M Lund, Kyle Koch, Snigdha Chatterjee, Erin R Alberts, Ryan E Martinez and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Michael BuscheLaboratory of Genetics, University of Wisconsin-Madison, Madison, WI 53706, USA.ORCID 0000-0001-8845-3300
Anne M RunkelDepartment of Plant and Microbial Biology, University of California, Berkeley, Berkeley, CA 94720, USA.ORCID 0000-0002-9777-2132
Min XuDepartment of Plant and Microbial Biology, University of California, Berkeley, Berkeley, CA 94720, USA.ORCID 0000-0002-7206-0059
Katherine A KlimpelLaboratory of Genetics, University of Wisconsin-Madison, Madison, WI 53706, USA.ORCID 0000-0001-7768-9457
Sannidhi MenonLaboratory of Genetics, University of Wisconsin-Madison, Madison, WI 53706, USA.ORCID 0009-0002-7868-6359
Katherine M LundLaboratory of Genetics, University of Wisconsin-Madison, Madison, WI 53706, USA.ORCID 0000-0001-6303-9314
Kyle KochLaboratory of Genetics, University of Wisconsin-Madison, Madison, WI 53706, USA.ORCID 0009-0003-4585-8561
Snigdha ChatterjeeLaboratory of Genetics, University of Wisconsin-Madison, Madison, WI 53706, USA.
Erin R AlbertsLaboratory of Genetics, University of Wisconsin-Madison, Madison, WI 53706, USA.ORCID 0000-0002-6319-4303
Ryan E MartinezLaboratory of Genetics, University of Wisconsin-Madison, Madison, WI 53706, USA.
M Regina ScarpinLaboratory of Genetics, University of Wisconsin-Madison, Madison, WI 53706, USA.ORCID 0000-0002-6454-7721
Jacob O BrunkardLaboratory of Genetics, University of Wisconsin-Madison, Madison, WI 53706, USA.ORCID 0000-0001-6407-9393

Funding

A tRNA synthetase is an amino acid sensor for TOR in plantsR01GM145814 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Jacob O Brunkard · 2022 to 2026
$1.8M
NIGMS NIH HHS R01 GM145814
6 · The paper itself

Abstract

Plant cells are connected by plasmodesmata (PD), membrane-lined channels that facilitate cell-to-cell transport. Forward genetic screens to uncover regulators of PD transport identified mutants with increased (

Indexed as

ArabidopsisArabidopsis ProteinsCell CommunicationGlucansGlucoseSignal TransductionTOR Serine-Threonine KinasesBasic-Leucine Zipper Transcription FactorsGene Expression Regulation, PlantMutationPhosphatidylinositol 3-KinasesPlasmodesmataArabidopsis ProteinsBasic-Leucine Zipper Transcription FactorscalloseGlucansGlucosePhosphatidylinositol 3-KinasesTOR protein, ArabidopsisTOR Serine-Threonine Kinases

Identifiers

PMID42696584
PMCPMC13544204

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.