ReviewCurrent cardiology reports2026
Circulating Biomarkers in Cardio-Oncology: Prediction and Prognostication.
Review in Current cardiology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewCirculating biomarkers are increasingly utilized in cardio-oncology for risk stratification, early detection, and prognostication of cancer therapy-related cardiovascular toxicity. This review summarizes the current evidence supporting established and emerging biomarkers, with a focus on their clinical utility and limitations. RECENT
findingsCardiac troponins and natriuretic peptides remain the most widely studied biomarkers, with troponins demonstrating consistently strong prognostic value and natriuretic peptides showing more variable predictive performance for cardiotoxicity. Emerging data highlight limitations in biomarker-guided therapeutic strategies, with inconsistent evidence for improved clinical outcomes. Novel biomarkers, including soluble suppression of tumorigenicity 2 (sST2), galectin-3, myeloperoxidase (MPO), inflammatory markers, and circulating microRNAs, show early promise for detecting subclinical injury through distinct pathophysiological pathways but lack standardization and validation for routine clinical use. Imaging biomarkers, including global longitudinal strain (GLS) and cardiac MRI parametric mapping, complement circulating markers and are increasingly integrated into surveillance strategies, with emerging randomized evidence supporting GLS-guided cardio-protection. Increasing emphasis has been placed on multimarker approaches and their integration with imaging and clinical context to improve diagnostic accuracy, although prospective validation of these strategies remains needed. Circulating biomarkers play an increasingly important role in contemporary cardio-oncology practice; however, no single biomarker is sufficient to guide management across all clinical scenarios. A multimodal strategy incorporating biomarkers, imaging, and clinical assessment is increasingly recommended. Future research should focus on standardization, validation of emerging biomarkers, and defining the role of biomarker-guided interventions to improve cardiovascular and cancer outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.