ArticleSleep & breathing = Schlaf & Atmung2026
Sleep disturbances, inflammation, and muscle function in older adults with sarcopenia.
Article in Sleep & breathing = Schlaf & Atmung, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Sleep Disturbances and Sarcopenia in Older Adults: Clinical Associations, Potential Mechanisms, and Management Strategies.International journal of general medicine · 2026Review
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionSarcopenia, a geriatric syndrome of muscle and functional loss that increases the risks of falls and mortality, may be aggravated by sleep disturbances that impair protein synthesis and promote catabolism via inflammation. The present study aimed to investigate the association between sleep patterns, inflammatory markers, and muscle function in older adults with and without sarcopenia.
methodsThis prospective controlled study included 63 older adults (> 65 years), classified into sarcopenic (ES, n = 31) and non-sarcopenic (ENS, n = 32) groups. Assessments included body composition, muscle function, inflammatory biomarkers, mood, and sleep (polysomnography, actigraphy, questionnaires).
resultsThe ES showed lower handgrip strength (21.7 ± 7.6 vs. 27.6 ± 10.4 kg; p < 0.05) and poorer physical performance (SPPB: 8.8 ± 2.3 vs. 11.2 ± 1.0; p < 0.05). They presented reduced thigh extension torque (82.7 ± 35.1 vs. 113.0 ± 26.8 N·m; p < 0.05) and flexion torque (44.4 ± 23.7 vs. 53.3 ± 16.0 N·m; p < 0.05). Sleep alterations included shorter total sleep time (p < 0.05), lower sleep efficiency (p < 0.05), higher WASO (p < 0.05), and increased apnea-hypopnea index (p < 0.05). TNF-α levels were higher in ES (p < 0.05). Mood disturbances were also greater, with lower vigor (p < 0.05) and higher TMD (p < 0.05).
conclusionSarcopenic older adults exhibit muscle impairments, sleep disturbances, and increased inflammation, which may accelerate sarcopenia progression, making sleep and inflammation important targets for intervention.
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