Evidence map›Paper›PMID 42696203›Full record

ArticleClinical journal of gastroenterology2026

Gastric mucosa-associated lymphoid tissue lymphoma diagnosed following localized gastric AL amyloidosis.

Mizuki Kameyama, Masaya Iwamuro, Takehiro Tanaka, Ayano Nishio, Chihiro Sakaguchi, Kenta Hamada, Yoshiyasu Kono, Yoshiro Kawahara, Shogen Ohya, Motoyuki Otsuka

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Article in Clinical journal of gastroenterology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Mizuki KameyamaCenter for Graduate Medical Education, Okayama University, Okayama, Japan.
Masaya IwamuroDepartment of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, 700-8558, Japan. iwamuromasaya@yahoo.co.jp.ORCID http://orcid.org/0000-0002-1757-5754
Takehiro TanakaDepartment of Pathology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Ayano NishioDepartment of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, 700-8558, Japan.
Chihiro SakaguchiDepartment of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, 700-8558, Japan.
Kenta HamadaDepartment of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, 700-8558, Japan.
Yoshiyasu KonoDepartment of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, 700-8558, Japan.
Yoshiro KawaharaDepartment of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, 700-8558, Japan.
Shogen OhyaKawaguchi Medical Clinic, Okayama, Japan.
Motoyuki OtsukaDepartment of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, 700-8558, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastrointestinal amyloidosis is a rare condition with diverse clinical and endoscopic manifestations. Among these subtypes, localized gastric AL amyloidosis is rare and associated with lymphoproliferative disorders. Here, we report a case of gastric mucosa-associated lymphoid tissue (MALT) lymphoma diagnosed during follow-up of localized gastric AL (κ) amyloidosis. A 65-year-old woman who underwent periodic endoscopic screening was found to have a localized erythematous lesion with erosion in the lower gastric body. Histopathological examination revealed amyloid deposits. Although potassium permanganate treatment suggested AA amyloidosis, immunohistochemical analysis confirmed AL (κ)-type amyloid. Systemic evaluation revealed no evidence of plasma cell dyscrasia, and localized gastric AL amyloidosis was diagnosed. After six months, the lesion regressed, but a newly identified discolored lesion was diagnosed as MALT lymphoma with plasmacytic differentiation. This case highlights the limitations of potassium permanganate-based amyloid typing and raises the possibility of an association between localized AL amyloidosis and lymphoproliferative disorders. These cases require careful endoscopic surveillance.

Indexed as

Amyloid typingGastric mucosa-associated lymphoid tissue lymphomaImmunohistochemistryLocalized gastric AL amyloidosisPotassium permanganate treatment

Identifiers

PMID42696203

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.