Evidence map›Paper›PMID 42696201›Full record

ArticleClinical journal of gastroenterology2026

Durable complete response following sequential atezolizumab-bevacizumab and delayed transcatheter arterial embolization in advanced hepatocellular carcinoma.

Daichi Takizawa, Keita Kiboshi, Yuki Tamura, Yumeo Tateyama, Mitsuhiko Shibasaki, Hiroki Tojima, Hirotaka Arai, Toshio Uraoka

Abstract read
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In one paragraph

Article in Clinical journal of gastroenterology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Daichi TakizawaDepartment of Gastroenterology, Maebashi Red Cross Hospital, Maebashi Japan, 389-1 Asakura-machi, Maebashi, Gunma, 371-0811, Japan. takizawa.biz@gmail.com.ORCID http://orcid.org/0000-0002-2004-8285
Keita KiboshiDepartment of Gastroenterology, Maebashi Red Cross Hospital, Maebashi Japan, 389-1 Asakura-machi, Maebashi, Gunma, 371-0811, Japan.
Yuki TamuraDepartment of Gastroenterology and Hepatology, Gunma University Graduate School of Medicine, Maebashi, Japan.
Yumeo TateyamaDepartment of Gastroenterology, Maebashi Red Cross Hospital, Maebashi Japan, 389-1 Asakura-machi, Maebashi, Gunma, 371-0811, Japan.
Mitsuhiko ShibasakiDepartment of Gastroenterology, Maebashi Red Cross Hospital, Maebashi Japan, 389-1 Asakura-machi, Maebashi, Gunma, 371-0811, Japan.
Hiroki TojimaDepartment of Gastroenterology and Hepatology, Gunma University Graduate School of Medicine, Maebashi, Japan.
Hirotaka AraiDepartment of Gastroenterology, Maebashi Red Cross Hospital, Maebashi Japan, 389-1 Asakura-machi, Maebashi, Gunma, 371-0811, Japan.
Toshio UraokaDepartment of Gastroenterology and Hepatology, Gunma University Graduate School of Medicine, Maebashi, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atezolizumab plus bevacizumab (ATZ/BEV) is an established first-line therapy for advanced hepatocellular carcinoma (HCC); however, complete response (CR) is rare. A man in his 70s was diagnosed with unresectable, multifocal HCC (maximum diameter, 190 mm) with vascular invasion. Liver function was preserved (Child-Pugh A, ALBI grade 1). ATZ/BEV was initiated, but the second cycle was postponed due to adverse events and intratumoral hemorrhage. Eight weeks later, selective transcatheter arterial embolization (TAE) was performed. Follow-up imaging showed disappearance of arterial enhancement in both embolized and non-embolized lesions. The patient has maintained CR for three years without additional treatment following sequential ATZ/BEV and selective TAE.

Indexed as

AtezolizumabBevacizumabComplete responseHepatocellular carcinomaTranscatheter arterial embolization

Identifiers

PMID42696201

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.