ArticleEuropean archives of psychiatry and clinical neuroscience2026
The role of alexithymia in the association between childhood maltreatment and depressive symptoms in Chinese men with methamphetamine use disorder.
Article in European archives of psychiatry and clinical neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundChildhood maltreatment (CM) is associated with depressive symptoms in methamphetamine use disorder (MAUD), but the emotional-processing mechanisms underlying this association remain unclear. Alexithymia may be particularly relevant, yet evidence from rehabilitation samples is limited. This study examined whether overall alexithymia and specific alexithymia dimensions showed statistical indirect associations between CM and depressive symptoms among men with MAUD.
methodsThis cross-sectional study included 605 Chinese men with MAUD recruited from a rehabilitation center. CM was measured using the Childhood Trauma Questionnaire-Short Form; participants meeting the moderate-to-severe threshold on at least one subscale were classified into the CM group (n = 348), and the remaining participants into the non-CM group (n = 257). Alexithymia was assessed using the Toronto Alexithymia Scale-20, including difficulty identifying feelings (DIF), difficulty describing feelings (DDF), and externally oriented thinking (EOT). Depressive symptoms were assessed using the Beck Depression Inventory-Short Form.
resultsThe CM group showed higher levels of depressive symptoms, overall alexithymia, and each alexithymia dimension than the non-CM group. Greater CM severity was positively associated with depressive symptoms, overall alexithymia, and each alexithymia dimension. Depressive symptoms were positively associated with overall alexithymia and its dimensions in the total sample and both groups. Furthermore, overall alexithymia showed a significant statistical indirect association between CM and depressive symptoms. In the parallel mediation model, only DIF showed a significant specific indirect association; DDF and EOT did not.
conclusionsCM was associated with greater alexithymia and depressive symptoms in men with MAUD. Overall alexithymia showed a modest statistical indirect association between CM and depressive symptoms, with DIF as the only dimension showing a significant specific indirect association.
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