Evidence map›Paper›PMID 42695617›Full record

ArticleChemistry & biodiversity2026

Two γ-Lactone Derivatives With Anti-Inflammatory Activities From a Mangrove Endophytic Fungus Alternaria sp. HN-17.

Yuru Sun, Bingbing Qian, Ruxue Mu, Zhongqian Xue, Linxuan Wu, Xin Huang, Yan Chen

Abstract read
In one paragraph

Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yuru Sun *School of Pharmacy, Anhui Medical University, Hefei, China.
Bingbing Qian *School of Pharmacy, Anhui Medical University, Hefei, China.
Ruxue MuSchool of Pharmacy, Anhui Medical University, Hefei, China.
Zhongqian XueSchool of Pharmacy, Anhui Medical University, Hefei, China.
Linxuan WuSchool of Pharmacy, Anhui Medical University, Hefei, China.
Xin HuangSchool of Pharmacy, Anhui Medical University, Hefei, China.
Yan ChenSchool of Pharmacy, Anhui Medical University, Hefei, China.ORCID https://orcid.org/0000-0002-2969-4072

Funding

National Natural Science Foundation of China 22577001the peak discipline Talents program, School of Pharmacy, Anhui Medical University 2023xktdzy1
6 · The paper itself

Abstract

Two γ-lactone derivatives, alterlactones A-B (1-2), along with one known analogue 3, were isolated from the mangrove endophytic fungus Alternaria sp. HN-17. Their structures were elucidated using comprehensive spectroscopic methods, including 1D and 2D NMR, HRESIMS, and electronic circular dichroism (ECD) calculations. Compounds 1 and 2 showed significant anti-inflammatory activity with IC

Indexed as

AlternariaAnti-Inflammatory AgentsAnti-Inflammatory Agents, Non-SteroidalLactonesAnimalsLipopolysaccharidesMiceMolecular ConformationMolecular StructureNitric OxideRAW 264.7 CellsStructure-Activity RelationshipAnti-Inflammatory AgentsAnti-Inflammatory Agents, Non-SteroidalLactonesLipopolysaccharidesNitric OxideAlternaria spanti‐inflammatoryendophytic fungus

Identifiers

PMID42695617
PMCPMC13543768

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.