Evidence map›Paper›PMID 42695433›Full record

ArticleInternational journal of oncology2026

Effect of xeroderma pigmentosum group C on the characteristics and regulatory mechanisms of lung cancer stem cells.

Ben Yang, Yang Yang, Weiyu Wang, Yubing Wang, Huaijie Wang, Liya Qin, Yongming Wang, Sipeng Sun, Shubo Wang, Meihua Qu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ben Yang *Translational Medical Center, Weifang Second People's Hospital, Weifang Respiratory Disease Hospital, Weifang, Shandong 261041, P.R. China.
Yang Yang *School of Public Health, Shandong Second Medical University, Weifang, Shandong 261053, P.R. China.
Weiyu WangDepartment of Otolaryngology and Head and Neck Surgery, Shandong Provincial ENT Hospital, Jinan, Shandong 250022, P.R. China.
Yubing WangTranslational Medical Center, Weifang Second People's Hospital, Weifang Respiratory Disease Hospital, Weifang, Shandong 261041, P.R. China.
Huaijie WangTranslational Medical Center, Weifang Second People's Hospital, Weifang Respiratory Disease Hospital, Weifang, Shandong 261041, P.R. China.
Liya QinTranslational Medical Center, Weifang Second People's Hospital, Weifang Respiratory Disease Hospital, Weifang, Shandong 261041, P.R. China.
Yongming WangTranslational Medical Center, Weifang Second People's Hospital, Weifang Respiratory Disease Hospital, Weifang, Shandong 261041, P.R. China.
Sipeng SunTranslational Medical Center, Weifang Second People's Hospital, Weifang Respiratory Disease Hospital, Weifang, Shandong 261041, P.R. China.
Shubo WangDepartment of Thoracic Surgery, Weifang Second People's Hospital, Weifang Respiratory Disease Hospital, Weifang, Shandong 261041, P.R. China.
Meihua QuTranslational Medical Center, Weifang Second People's Hospital, Weifang Respiratory Disease Hospital, Weifang, Shandong 261041, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung cancer is one of the most common and deadly forms of cancer worldwide, with >80% of cases being non‑small cell lung cancer. Its recurrence and drug resistance have been major challenges in clinical treatment, posing a serious threat to the lives of patients. The present study found that high xeroderma pigmentosum group C (XPC) expression markedly reduced the proliferation capacity and stem cell characteristics of the lung cancer cell lines A549‑XPC and H460‑XPC. In addition, XPC overexpression led to a decreased in the proportion of cells in the G

Indexed as

Carcinoma, Non-Small-Cell LungDNA-Binding ProteinsLung NeoplasmsNeoplastic Stem CellsXeroderma PigmentosumA549 CellsAnimalsCell Line, TumorCell ProliferationDrug Resistance, NeoplasmFemaleGene Expression Regulation, NeoplasticHumansMaleMiceSignal TransductionDNA-Binding ProteinsXPC protein, humanchemotherapyJAK/STAT signaling pathwaylung cancer stem cellxeroderma pigmentosum group C

Identifiers

PMID42695433
PMCPMC13553190

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.