ArticleVeterinary ophthalmology2026
Measurement of Anions in Dog Tear Fluid Using Ion Chromatography.
Article in Veterinary ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
objectiveAnions in tears may be related to the pathogenesis of ocular surface diseases. A comprehensive method that can detect small quantities of anions in human tears has been developed. However, the differences in individual anion concentrations between tears and plasma remain unclear. This study investigated anion concentrations in dog tears.
methodsTo compare anion concentrations between tear and plasma samples in canines, 12 eyes of six healthy purpose-bred research Beagles (unneutered males, 3 years old) were investigated. Additionally, the tears of canines with various diseases were examined. PROCEDURE: Anion concentrations were assessed using a commercially available ion chromatography system. For this, at least 10 μL of tears were collected in a glass capillary tube and diluted with 300 μL of distilled water; plasma was obtained by centrifuging collected blood samples, which were then diluted 100-fold before chromatography.
resultsAnion concentrations differed significantly between the tears and plasma of Beagles. The average concentrations (mg/L) of anions in tears of Beagles were as follows: Cl
conclusionsHerein, we observed that certain anions, such as Br
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