ArticlePediatric transplantation2026
Effects of Perioperative Management on Short-Term Renal Transplant Outcome: A Retrospective Cohort Study.
Article in Pediatric transplantation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
backgroundThere are limited data on how intraoperative hemodynamic factors influence pediatric kidney transplant outcomes, particularly across the different phases of graft reperfusion. With the widespread introduction of anesthesia information management systems, new opportunities have emerged to explore how intraoperative management affects transplant outcomes.
methodsWe conducted a retrospective cohort study at a single center, including transplant recipients under 19 years of age who underwent kidney transplantation between 2010 and 2022 (n = 121). Data were extracted from chart reviews, anesthesia records, and an intraoperative monitoring databank. Modeling for clinical variables alone, intraoperative variables alone, and combined clinical-intraoperative features was analyzed with respect to three outcomes: Unadjusted glomerular filtration rate at one-month post-transplant (uGFR
resultsLonger duration of pre-unclamp mean arterial pressure (MAP) below the 95th percentile (β = -0.086, p = 0.009), a greater number of inotropes used during the pre-unclamp period (β = -4.00, p = 0.017), and higher MAP variability in the first 30 min post-unclamp (β = -1.38, p = 0.006) were each independently associated with lower uGFR
conclusionsIntraoperative features related to pre-unclamp volume resuscitation, MAP control, and post-unclamp hemodynamic instability are associated with slower graft function in pediatric kidney transplantation.
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