Evidence map›Paper›PMID 42695082›Full record

ArticleCureus2026

SMARCA4-Deficient Undifferentiated Tumor of the Right Colon in a Patient With Ulcerative Colitis.

Elizabeth Reynolds, Fergus Reid, Rawan ElManfalouty, Ahmed Holayel, Shailesh Agrawal, Konstantinos Kamposioras

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Elizabeth ReynoldsDepartment of Surgery, East Lancashire Hospitals NHS Trust, Blackburn, GBR.
Fergus ReidDepartment of Surgery, Stockport NHS Foundation Trust, Stockport, GBR.
Rawan ElManfaloutyDepartment of Medical Oncology, The Christie NHS Foundation Trust, Manchester, GBR.
Ahmed HolayelDepartment of Oncology, University Hospitals of Leicester NHS Trust, Leicester, GBR.
Shailesh AgrawalDepartment of Pathology, Stockport NHS Foundation Trust, Stockport, GBR.
Konstantinos KamposiorasDepartment of Medical Oncology, The Christie NHS Foundation Trust, Manchester, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Undifferentiated gastrointestinal tumors with SMARCA4 deficiency are a rare subset of malignancies that often present as advanced, rapidly progressive disease. SMARCA4 loss is identified by immunohistochemistry, and affected tumors demonstrate distinct morphological features. Ulcerative colitis is a chronic inflammatory disorder that predisposes patients to colitis-associated colorectal cancer through a variety of genetic alterations. We present the case of a 31-year-old patient with a SMARCA4-deficient undifferentiated right-sided colon cancer detected during surveillance colonoscopy for ulcerative colitis. We also review the potential association between ulcerative colitis and SMARCA4-deficient undifferentiated gastrointestinal tumors.

Indexed as

colorectal cancerfolfoxirigastrointestinal obstructionsubtotal abdominal colectomyulcerative colitis

Identifiers

PMID42695082
PMCPMC13541087

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.