Evidence map›Paper›PMID 42695034›Full record

ArticleSurgical neurology international2026

Cyberknife radiosurgery for hemifacial spasm.

Hussein Hamdi, Ibrahim Gheit, Ayman M Al-Malt, Shaima Shoeir, Azza Nasr, Azza Taher, Mohamed Zaghloul, Hany Ammar

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Article in Surgical neurology international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hussein HamdiDepartment of Neurosurgery, Tanta University, Tanta, Egypt.
Ibrahim GheitDepartment of Neuroscience, Wayne state University, Michigan, USA.
Ayman M Al-MaltNeurology Department, Tanta University, Tanta, Egypt.
Shaima ShoeirChildren Cancer Hospital Egypt, Cairo, Radiation Oncology Department, National Cancer Institute, Cairo University, Cairo, Egypt.
Azza NasrChildren Cancer Hospital Egypt, Cairo, Radiation Oncology Department, National Cancer Institute, Cairo University, Cairo, Egypt.
Azza TaherChildren Cancer Hospital Egypt, Cairo, Radiation Oncology Department, National Cancer Institute, Cairo University, Cairo, Egypt.
Mohamed ZaghloulChildren Cancer Hospital Egypt, Cairo, Radiation Oncology Department, National Cancer Institute, Cairo University, Cairo, Egypt.
Hany AmmarChildren Cancer Hospital Egypt, Cairo, Radiation Oncology Department, National Cancer Institute, Cairo University, Cairo, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Surgical management of hemifacial spasm (HFS) may be contraindicated in medically unfit patients or declined because of the potential risks associated with surgery. Therefore, minimally invasive and non-invasive alternatives merit investigation. This preliminary study aims to evaluate the safety, efficacy, and optimal technical parameters of CyberKnife radiosurgery for HFS. Methods: We present the first observational study using CyberKnife for HFS in non-tumor HFS cases, including idiopathic, vascular, post-COVID, post-palsy, and co-existing trigeminal neuralgia (TN). An extensive literature review was conducted. Results: CyberKnife radiosurgery resulted in significant reductions in the severity, frequency, and duration of HFSs, increased voluntary suppressibility, with clinical improvement typically observed within a short time frame and without treatment-related complications. Trigger-induced spasms were markedly reduced, while continuous spasms showed the greatest responsiveness to treatment. A parallel improvement in HFS and TN was noted. This literature review has enabled us to identify and discuss optimal radiation doses and targeting strategies for this novel technique in treating HFS, providing clearer radiosurgical parameters for future studies. Conclusion: The results indicate efficacy and safety with the recommended radiosurgical parameters for treating various types of HFS through radiosurgery. We encourage larger studies to establish robust, comprehensive evidence, particularly in patients with coexisting TN.

Indexed as

CyberknifeGamma KnifeHemifacial spasmMicrovascular decompressionNon-invasiveRadiosurgery

Identifiers

PMID42695034
PMCPMC13541036

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