ArticleDEN open2027
Endoscopic Injection Sclerotherapy With Pre-deflation Ligation for Prolonged Sclerosant Retention in Esophageal Varices: A Case Report.
Article in DEN open, 2027. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Esophageal varices are a common complication of portal hypertension, and prophylactic endoscopic injection sclerotherapy with ligation (EISL) is an established treatment option. Effective variceal thrombosis requires sufficient intravariceal retention of the sclerosant, because ethanolamine oleate exerts its thrombogenic effect through prolonged contact with the venous endothelium. In conventional EISL, endoscopic variceal ligation (EVL) is performed after balloon deflation, leaving a transient interval during which restored blood flow and an open puncture site may permit washout of the sclerosant and bleeding. We describe EIS with pre-deflation ligation (EISpdL), in which EVL of the puncture site is completed while the endoscope balloon remains inflated, and balloon compression is maintained throughout the retention period. A 59-year-old man with medium-sized esophageal varices with a positive red color sign (F2, RC1) secondary to metabolic dysfunction-associated steatohepatitis underwent EISpdL combined with gel-immersion EIS. The procedure was technically feasible, required no additional skills beyond conventional EISL, and no immediate procedure-related adverse events were observed. Follow-up endoscopy on post-procedure day 7 showed bronze-colored variceal changes indicating thrombosis, and contrast-enhanced computed tomography two months later confirmed obliteration. EISpdL may enable more stable and prolonged sclerosant retention.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.