Evidence map›Paper›PMID 42694754›Full record

ReviewFrontiers in ophthalmology2026

SPECT/CT imaging in thyroid eye disease: an emerging role in assessing sub-clinical activity.

Kelsey A Roelofs, Kimberly M Papp, Kate S Lim, Ezekiel Weis

Abstract readReview
In one paragraph

Review in Frontiers in ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kelsey A RoelofsDepartment of Ophthalmology and Visual Sciences, University of Alberta, Edmonton, AB, Canada.
Kimberly M PappDepartment of Ophthalmology, University of British Columbia, Vancouver, BC, Canada.
Kate S LimDepartment of Ophthalmology and Visual Sciences, University of Alberta, Edmonton, AB, Canada.
Ezekiel WeisDepartment of Ophthalmology and Visual Sciences, University of Alberta, Edmonton, AB, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thyroid eye disease (TED) diagnosis is made based on the presence of a constellation of clinical, laboratory, and radiologic findings. Currently, computed tomography (CT) and magnetic resonance imaging (MRI) are the most commonly used imaging modalities; however, they provide indirect indicators of underlying inflammation, resulting in limited specificity. Our narrative review explored the role of Single Photon Emission Computed Tomography (SPECT)/CT in TED with the goal of enhancing our ability to correlate structure with function in TED. A non-systematic narrative search of major electronic databases was conducted to identify literature on SPECT/CT in TED, using targeted selection and thematic narrative synthesis to analyze the findings. Technetium-99m diethylenetriaminepentaacetic acid (

Indexed as

clinical activity score (CAS)graves orbitopathyorbital imagingSPECT/CTthyroid eye diseasethyroid orbitopathy

Identifiers

PMID42694754
PMCPMC13539554

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.