Evidence map›Paper›PMID 42694744›Full record

ArticleISME communications2026

Metabolome restructuring reveals distinct virocell infection strategies in bacteriophage-host interaction.

Sumudu Rajakaruna, Cristina Howard-Varona, Marion Urvoy, Roya AminiTabrizi, Christian Ayala-Ortiz, Marissa Gittrich, Natalie Solonenko, Marie Burris, Courtney Sanderson, Cara Noel and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ISME communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Sumudu RajakarunaDepartment of Environmental Science, University of Arizona, Tucson, AZ 85721, United States.ORCID https://orcid.org/0000-0003-1836-3726
Cristina Howard-VaronaDepartment of Microbiology, The Ohio State University, Columbus, OH 43210, United States.ORCID https://orcid.org/0000-0002-4149-5818
Marion UrvoyDepartment of Microbiology, The Ohio State University, Columbus, OH 43210, United States.
Roya AminiTabriziDepartment of Environmental Science, University of Arizona, Tucson, AZ 85721, United States.
Christian Ayala-OrtizDepartment of Environmental Science, University of Arizona, Tucson, AZ 85721, United States.
Marissa GittrichDepartment of Microbiology, The Ohio State University, Columbus, OH 43210, United States.
Natalie SolonenkoDepartment of Microbiology, The Ohio State University, Columbus, OH 43210, United States.
Marie BurrisDepartment of Microbiology, The Ohio State University, Columbus, OH 43210, United States.
Courtney SandersonDepartment of Microbiology, The Ohio State University, Columbus, OH 43210, United States.
Cara NoelDepartment of Microbiology, The Ohio State University, Columbus, OH 43210, United States.
Jonathan LeopoldDepartment of Microbiology, The Ohio State University, Columbus, OH 43210, United States.
Lillyanna QuillinDepartment of Microbiology, The Ohio State University, Columbus, OH 43210, United States.
Kush DoshiDepartment of Biochemistry, The Ohio State University, Columbus, OH 43210, United States.
Lawrence R WalkerAnalytical and Biological Mass Spectrometry Facility, University of Arizona, Tucson, AZ 85721, United States.
Matthew B SullivanDepartment of Microbiology, The Ohio State University, Columbus, OH 43210, United States.
Malak M TfailyDepartment of Environmental Science, University of Arizona, Tucson, AZ 85721, United States.ORCID https://orcid.org/0000-0002-3036-2833

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viral infection transforms microbial cells into metabolically reprogrammed "virocells," yet the metabolic architecture underlying this transition remains poorly resolved. Here we investigate how bacteriophages reshape host metabolism in

Indexed as

bacteriophage-host interactionsCellulophaga balticainfection efficiencymarine heterotrophic bacteriametabolic reprogrammingmetabolite annotationmultivariate metabolomicstemporal metabolic dynamicsuntargeted metabolomicsvirocell

Identifiers

PMID42694744
PMCPMC13540731

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.