Evidence map›Paper›PMID 42694670›Full record

ArticleInfection and drug resistance2026

Fatal Tension Pneumocephalus Associated with Central Nervous System Infection Caused by an Extended-Spectrum β-Lactamase-Producing

Xianyu Zhu, Ying Gao, Jiayan Zhang, Lifeng Sun, Min Peng, Yan Cui, Keliang Xie

Abstract readCase Reports
In one paragraph

Article in Infection and drug resistance, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xianyu Zhu *Department of Critical Care Medicine, Tianjin Medical University General Hospital, Tianjin, 300052, People's Republic of China.ORCID 0009-0002-8148-2090
Ying Gao *Department of Critical Care Medicine, Tianjin Medical University General Hospital, Tianjin, 300052, People's Republic of China.ORCID 0000-0002-8050-9231
Jiayan ZhangDepartment of Critical Care Medicine, Tianjin Medical University General Hospital, Tianjin, 300052, People's Republic of China.
Lifeng SunDepartment of Critical Care Medicine, Tianjin Medical University General Hospital, Tianjin, 300052, People's Republic of China.ORCID 0009-0000-6354-5700
Min PengDepartment of Critical Care Medicine, Tianjin Medical University General Hospital, Tianjin, 300052, People's Republic of China.
Yan CuiDepartment of Critical Care Medicine, Tianjin Medical University General Hospital, Tianjin, 300052, People's Republic of China.
Keliang XieDepartment of Critical Care Medicine, Tianjin Medical University General Hospital, Tianjin, 300052, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Central nervous system (CNS) infections caused by Case Presentation: We report a fatal case of a 49-year-old female with a 40-year history of polycystic liver and kidney disease who presented with fulminant meningoencephalitis. Despite aggressive systemic meropenem therapy and neuroprotective measures, she developed refractory intracranial hypertension (780 mmH Conclusion: The rapid evolution of tension pneumocephalus in this case highlights the potential for abrupt neurological deterioration in CNS infections associated with convergent

Indexed as

extended-spectrum beta-lactamasehypervirulence-associated genesKlebsiella pneumoniaemeningoencephalitismetagenomic next-generation sequencingtension pneumocephalus

Identifiers

PMID42694670
PMCPMC13540577

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.