Evidence map›Paper›PMID 42694587›Full record

ArticleAlpha psychiatry2026

Artificial Intelligence Chatbot Dependence, Anxiety, and Depressive Symptoms in University Students: Initial Psychometric Evaluation of the Artificial Intelligence Chatbot Dependence Scale (AICDS) in Spanish.

Iván Barrios, Julio Torales, Sandra Blanco, Carlos Manuel Giménez-Barboza, Brenda Mikaela Monges-Guerrero, Axel Verón-Otero, Gladys Mercedes Estigarribia Sanabria, Eva Natalia Giménez-Legal, João Mauricio Castaldelli-Maia, Antonio Ventriglio

Abstract read
In one paragraph

Article in Alpha psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Iván BarriosCátedra de Metodología de la Investigación II, Filial Santa Rosa del Aguaray, Facultad de Ciencias Médicas, Universidad Nacional de Asunción, 111421 Santa Rosa del Aguaray, Paraguay.ORCID https://orcid.org/0000-0002-6843-7685
Julio ToralesFaculty of Health Sciences, Universidad Sudamericana, 7800 Salto del Guairá, Paraguay.ORCID https://orcid.org/0000-0003-3277-7036
Sandra BlancoCátedra de Metodología de la Investigación II, Filial Santa Rosa del Aguaray, Facultad de Ciencias Médicas, Universidad Nacional de Asunción, 111421 Santa Rosa del Aguaray, Paraguay.ORCID https://orcid.org/0009-0003-2041-8498
Carlos Manuel Giménez-BarbozaCátedra de Metodología de la Investigación II, Filial Santa Rosa del Aguaray, Facultad de Ciencias Médicas, Universidad Nacional de Asunción, 111421 Santa Rosa del Aguaray, Paraguay.ORCID https://orcid.org/0009-0005-8069-1132
Brenda Mikaela Monges-GuerreroCátedra de Metodología de la Investigación II, Filial Santa Rosa del Aguaray, Facultad de Ciencias Médicas, Universidad Nacional de Asunción, 111421 Santa Rosa del Aguaray, Paraguay.ORCID https://orcid.org/0009-0004-1847-296X
Axel Verón-OteroCátedra de Metodología de la Investigación II, Filial Santa Rosa del Aguaray, Facultad de Ciencias Médicas, Universidad Nacional de Asunción, 111421 Santa Rosa del Aguaray, Paraguay.ORCID https://orcid.org/0009-0006-2890-4281
Gladys Mercedes Estigarribia SanabriaCátedra de Metodología de la Investigación II, Filial Santa Rosa del Aguaray, Facultad de Ciencias Médicas, Universidad Nacional de Asunción, 111421 Santa Rosa del Aguaray, Paraguay.ORCID https://orcid.org/0000-0001-8058-9369
Eva Natalia Giménez-LegalGrupo de Investigación sobre Epidemiología de los Trastornos Mentales, Psicopatología y Neurociencias, Facultad de Ciencias Médicas, Universidad Nacional de Asunción, 111421 San Lorenzo, Paraguay.ORCID https://orcid.org/0000-0003-4426-4182
João Mauricio Castaldelli-MaiaDepartment of Psychiatry, University of São Paulo, São Paulo, SP 05403-903, Brazil.ORCID https://orcid.org/0000-0001-9621-2291
Antonio VentriglioDepartment of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy.ORCID https://orcid.org/0000-0002-3934-7007

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Artificial intelligence (AI) chatbots are rapidly becoming integrated into higher education, supporting human-computer interaction, knowledge explanation, rapid access to information, access to online learning resources, and personalized learning pathways. However, little is known about potential patterns of dependence on these technologies and their relationship with anxiety and depressive symptoms. This study aimed to conduct an initial psychometric evaluation of the Spanish version of the Artificial Intelligence Chatbot Dependence Scale (AICDS) and to explore its association with anxiety and depressive symptoms among university students. Methods: A cross-sectional study was conducted among 200 university students from Santa Rosa del Aguaray, Paraguay. Participants completed the AICDS together with screening measures of anxiety and depressive symptoms. Data were analyzed using R version 4.5.3. Confirmatory factor analysis using diagonally weighted least squares estimation with robust standard errors was performed to examine the scale's factor structure, and multiple linear regression models were used to evaluate associations between AICDS scores and anxiety and depressive symptoms. Results: The findings supported a unidimensional factor structure with acceptable-to-good model fit and high internal consistency (Cronbach's α = 0.833; McDonald's ω = 0.903). Fully standardized factor loadings ranged from 0.538 to 0.873. In bivariate analyses, students who screened positive for anxiety symptoms had higher AICDS scores than those who screened negative, although the effect size was small. However, this association was not maintained after adjustment for sociodemographic and academic covariates in multiple regression models. No significant association was observed between AICDS scores and depressive symptoms under two-tailed testing. Conclusions: These findings provide preliminary evidence supporting the internal consistency and factorial validity of the Spanish version of the AICDS in this sample. However, associations between AI chatbot dependence and anxiety or depressive symptoms were weak and not robust after adjustment. Further longitudinal and psychometric research is needed before broader conclusions can be drawn about the mental health implications of AI chatbot dependence among university students.

Indexed as

anxietyartificial intelligencechatbotsdepressive symptomsmental healthuniversity students

Identifiers

PMID42694587
PMCPMC13540032

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.