ArticleCureus2026
Effects of a Sound-Based Meditative Intervention on Anxiety, Depression, Salivary Cortisol Levels, and Blood Pressure: A Randomized Controlled Trial.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
2 authors.
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Abstract
Background Psychological stress contributes to mental health symptoms and cardiovascular risk through pathways involving anxiety, depression, cortisol secretion, autonomic dysregulation, and elevated blood pressure. Sound-based meditation is a nonpharmacological approach that may support stress management, but randomized controlled trial evidence remains limited. Objective The objective was to evaluate whether a structured sound-based meditation intervention was associated with lower post-intervention anxiety symptoms, measured using the Hospital Anxiety and Depression Scale-Anxiety subscale (HADS-A), than a remotely delivered music-control condition after four weeks. Depressive symptoms, salivary cortisol concentration, systolic blood pressure, and exploratory diastolic blood pressure were also assessed. Methodology This parallel-group randomized controlled trial enrolled 100 adults aged 21-65 years from meditation centers and surrounding communities in Tamil Nadu, India. Participants were randomly assigned in a 1:1 ratio to a sound-based meditation intervention group (
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