Evidence map›Paper›PMID 42694457›Full record

ArticlemicroPublication biology2026

The effects of obesogenic diet on a

Charlie Ake, Eric Cervantes, Christal Garcia, Hannah Hammons, Lisa Obawole, Isabella Morton, Lexie Pham, Brandon Salas, Sadie Stacks, Luis Villarreal and 6 more

Abstract read
In one paragraph

Article in microPublication biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Charlie AkeBiology, Texas A&M University, College Station, TX, US.
Eric CervantesBiology, Texas A&M University, College Station, TX, US.
Christal GarciaBiology, Texas A&M University, College Station, TX, US.
Hannah HammonsBiology, Texas A&M University, College Station, TX, US.
Lisa ObawoleBiology, Texas A&M University, College Station, TX, US.
Isabella MortonBiology, Texas A&M University, College Station, TX, US.
Lexie PhamBiology, Texas A&M University, College Station, TX, US.
Brandon SalasBiology, Texas A&M University, College Station, TX, US.
Sadie StacksBiology, Texas A&M University, College Station, TX, US.
Luis VillarrealBiology, Texas A&M University, College Station, TX, US.
Faith YorkBiology, Texas A&M University, College Station, TX, US.
Samaneh BiglariBiology, Texas A&M University, College Station, TX, US.
Eshani YeragiBiology, Texas A&M University, College Station, TX, US.
Elizabeth LillvisBiology, Texas A&M University, College Station, TX, US.
Matthew Moulton *Biology, Texas A&M University, College Station, TX, US.
Alex Keene *Biology, Texas A&M University, College Station, TX, US.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tau aggregation is a hallmark of neurodegenerative diseases including Alzheimer's disease and frontotemporal dementia. Here, we tested how an obesogenic diet affects a Drosophila tauopathy model across multiple behavioral assays. In group-housed flies, mutant tau shortened lifespan, and this effect was worsened by a high-sugar diet. We also examined sleep, motor behavior, and sensory responsiveness. Tau-expressing flies differed from controls in all assays, but these deficits were not further exacerbated by diet. These findings reveal assay-specific diet effects and highlight the value of using multiple behavioral measures to characterize tau mutant phenotypes.

Identifiers

PMID42694457
PMCPMC13539387

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.