Evidence map›Paper›PMID 42694376›Full record

ArticleFrontiers in bioengineering and biotechnology2026

Biomechanical impact of severe genu valgum (18°) on the lateral meniscus: a finite element stress analysis.

Miguel Angel García-Laguna, Guillermo Urriolagoitia-Sosa, Beatriz Romero-Ángeles, Miguel Martinez-Mondragon, Jorge Alberto Gomez-Niebla, Luis Itzcoatl Lugo-Chacon, Alfonso Trejo-Enríquez, Jonathan Mireles-Hernández, Francisco Javier Gallegos-Funes, Erick Velazquez-Lozada

Abstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Miguel Angel García-LagunaInstituto Politécnico Nacional, Escuela Superior de Ingeniería Mecánica y Eléctrica, Sección de Estudios de Posgrado e Investigación, Unidad Profesional Adolfo López Mateos Zacatenco, Ciudad de México, Mexico.
Guillermo Urriolagoitia-SosaInstituto Politécnico Nacional, Escuela Superior de Ingeniería Mecánica y Eléctrica, Sección de Estudios de Posgrado e Investigación, Unidad Profesional Adolfo López Mateos Zacatenco, Ciudad de México, Mexico.
Beatriz Romero-ÁngelesInstituto Politécnico Nacional, Escuela Superior de Ingeniería Mecánica y Eléctrica, Sección de Estudios de Posgrado e Investigación, Unidad Profesional Adolfo López Mateos Zacatenco, Ciudad de México, Mexico.
Miguel Martinez-MondragonInstituto Politécnico Nacional, Escuela Superior de Ingeniería Mecánica y Eléctrica, Sección de Estudios de Posgrado e Investigación, Unidad Profesional Adolfo López Mateos Zacatenco, Ciudad de México, Mexico.
Jorge Alberto Gomez-NieblaInstituto Politécnico Nacional, Escuela Superior de Ingeniería Mecánica y Eléctrica, Sección de Estudios de Posgrado e Investigación, Unidad Profesional Adolfo López Mateos Zacatenco, Ciudad de México, Mexico.
Luis Itzcoatl Lugo-ChaconInstituto Politécnico Nacional, Escuela Superior de Ingeniería Mecánica y Eléctrica, Sección de Estudios de Posgrado e Investigación, Unidad Profesional Adolfo López Mateos Zacatenco, Ciudad de México, Mexico.
Alfonso Trejo-EnríquezInstituto Politécnico Nacional, Escuela Superior de Ingeniería Mecánica y Eléctrica, Sección de Estudios de Posgrado e Investigación, Unidad Profesional Adolfo López Mateos Zacatenco, Ciudad de México, Mexico.
Jonathan Mireles-HernándezInstituto Politécnico Nacional, Escuela Superior de Ingeniería Mecánica y Eléctrica, Sección de Estudios de Posgrado e Investigación, Unidad Profesional Adolfo López Mateos Zacatenco, Ciudad de México, Mexico.
Francisco Javier Gallegos-FunesInstituto Politécnico Nacional, Escuela Superior de Ingeniería Mecánica y Eléctrica, Sección de Estudios de Posgrado e Investigación, Unidad Profesional Adolfo López Mateos Zacatenco, Ciudad de México, Mexico.
Erick Velazquez-LozadaInstituto Politécnico Nacional, Escuela Superior de Ingeniería Mecánica y Eléctrica, Sección de Estudios de Posgrado e Investigación, Unidad Profesional Adolfo López Mateos Zacatenco, Ciudad de México, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genu valgum is a deformity that alters load transmission in the knee. While the effects of mild deviations are known, the specific quantitative impact of severe deformities (>15°) on the lateral meniscus remains understudied. This research aims to quantify the stress distribution in a severe 18° valgus deformity compared to a healthy morphology. A comparative Finite Element Analysis (FEA) was conducted. 3D models were reconstructed from segmented DICOM images using MIMICS and 3MATIC software. A static vertical load of 850 N, simulating a bipedal stance, was applied to both a healthy model and a pathological model with an 18° axial deviation. The simulation used a high-order 20-node quadratic mesh to ensure accurate capture of stress gradients. The healthy knee exhibited a maximum Von Mises stress of 2.76 MPa, distributed homogeneously. In contrast, the pathological model showed a critical stress concentration of 17.54 MPa in the lateral meniscus. This represents a 535% increase, demonstrating a non-linear exponential rise in stress compared to milder deformities reported in the literature. An 18° valgus deformity subjects the lateral meniscus to stress levels exceeding physiological fatigue limits, confirming the mechanism for the rapid onset of lateral unicompartmental osteoarthritis. These findings suggest that conservative therapies are biomechanically insufficient for such degrees of deformity, validating the necessity for corrective osteotomy and the use of FEA as a preoperative planning tool.

Indexed as

finite element analysisgenu valgumknee biomechanicsmeniscusosteoarthritis

Identifiers

PMID42694376
PMCPMC13538425

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.