ArticleFrontiers in pediatrics2026
Clinical and epidemiological profiles of six respiratory pathogens in hospitalized children in Lixin County, Anhui, China (2024-2025).
Article in Frontiers in pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Acute respiratory infections are caused by a diverse range of pathogens. This study aimed to investigate the epidemiological profiles and clinical features of major respiratory pathogens by analyzing their detection rates in hospitalized pediatric patients. Methods: Nasopharyngeal swab specimens were retrospectively enrolled from pediatric inpatients diagnosed with acute respiratory infections at the Department of Pediatrics, Lixin County People's Hospital, between February 2024 and August 2025. All specimens were subjected to polymerase chain reaction (PCR) assays targeting six major respiratory pathogens, namely adenovirus, respiratory syncytial virus, influenza A virus, influenza B virus, parainfluenza virus, and Results: The epidemiological and clinical profiles of the six detected respiratory pathogens are summarized below. In brief, the overall positivity rate of pathogens exhibited winter-spring predominance, with adenovirus and RSV showing the broadest outbreak windows (November-July and November-May, respectively), while influenza A was more restricted (December-March). Conclusion: During the winter season, multiple respiratory pathogens tend to circulate actively. Acute respiratory infections caused by different pathogens exhibit distinct age distributions and clinical manifestations. These features, when combined with local epidemiological data, may assist clinicians in promptly identifying the likely causative pathogen.
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