ArticleJournal of the Endocrine Society2026
Skin symptoms and their impact on quality-of-life in adults with osteogenesis imperfecta.
Article in Journal of the Endocrine Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
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0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Osteogenesis imperfecta (OI) is a genetic connective tissue disorder caused by abnormalities in type I collagen, which is abundant in skin. Yet, data on dermatologic manifestations and their impact on quality-of-life (QOL) are limited. This study evaluated the prevalence of skin symptoms in adults with OI compared with adults without OI and assessed their effect on QOL. In this cross-sectional, survey-based study, adults with OI were recruited via US and European OI foundations, and comparators were recruited from an Oregon Health & Science University research registry. Participants completed a 20-item skin symptom questionnaire; those reporting bothersome or itchy skin also completed validated QOL instruments (Skindex-29 and ItchyQoL). Group and severity-stratified comparisons were analyzed using t-tests, chi-square tests, and analysis of variance (
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